Zepym Health
Semax + Selank

Injected under the skin · 5 days a week

Research peptideCognitionStress

Semax + Selank

Semax (nootropic, ACTH analog) + Selank (anxiolytic, tuftsine analog): studied in Russia and Eastern Europe for focus, stress resilience, and calm. Intranasal spray or subcutaneous injection. Broad evidence outside the Western clinic; early-stage in the US.

  • Semax for cognitive focus and mental clarity
  • Selank for anxiety reduction and mood support
  • Intranasal or injected; used widely in Russia; Western evidence emerging
  • Monthly$329/mo
  • Every 3 months$777 billed up front$259/mo
  • Every 6 monthsBest value$1,374 billed up front$229/mo
  • Free, discreet shipping
  • Licensed U.S. pharmacy
  • Board-certified physicians

Disclaimer: Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Compounded medications are not FDA-approved brand-name products.

How
Injected under the skin
How often
5 days a week
Each shipment
1 vial
Strength
1 mg / 1 mg/mL

What is Semax + Selank?

(synthetic ACTH analog + tuftsine analog)

Semax is a synthetic analog of ACTH (adrenocorticotropic hormone) studied as a nootropic for focus and mental endurance. Selank is a synthetic analog of tuftsine, an immune peptide with anxiolytic (anti-anxiety) effects. Both are given as intranasal sprays or subcutaneous injections. Widely used in Russia and Eastern Europe; growing clinical interest in the West, but US trials are limited.

What's in it

  • SemaxStudied for focus and memory
  • SelankStudied for calm and stress

Russian/Eastern European

extensive use and research; Western clinical trials limited

Semax and Selank are prescribed off-label. Semax has human data from Russian studies; Selank evidence is solid in anxiety models. Your physician weighs the geographic evidence gap.

Is it right for you?

  • Who it's for

    Adults who want support for focus and calm during demanding periods.

  • What sets it apart

    Two peptides from Russian medicine, where they are used as nasal drops: Semax for attention, Selank for anxiety.

  • Worth knowing before you start

    Inject it in the morning. Late in the day it can interfere with sleep.

What to expect

  • Patience required

    early-stage therapies take time; effects build over weeks

  • Improved sleep or mood

    tracking with a journal helps you see the changes

  • Better focus or calm

    cognitive clarity or reduced stress as peptides work

  • Physician partnership

    close communication ensures your safety and response

How neuro peptides work

  1. Day 1

    A US-licensed physician reviews your sleep, mood, or cognitive goals, health history, and current medications. Discusses how these early-stage peptides work and the evidence gaps.

    1
  2. Week 1

    Start with a subcutaneous injection or intranasal spray at bedtime (or as directed). Most people find the routine comfortable within days.

    2
  3. Weeks 2–4

    Sleep quality, mood, or focus may begin to shift. Some notice changes within days; others take 3–4 weeks. Keep a sleep or mood journal.

    3
  4. Month 2

    Your physician checks in, reviews your journal, and adjusts dose if needed. Discuss any changes in sleep, mood, energy, or focus.

    4
  5. Beyond

    Neuro peptides work best with consistent use. Your physician monitors your response every 4–6 weeks and adjusts as your needs change.

    5

Individual results vary. Benefits reflect what Zepym Health members commonly report to their physician at check-ins; they are not the results of a clinical trial.

How you use it

This is the starting dose the pharmacy prints on the label. Your physician sets yours and adjusts it with you.

How
Injected under the skin
Dose
20 units (0.2 mg)
How often
5 days a week
When
In the morning
Each shipment
1 vial
Pharmacy label
Inject 20 units (0.2 mg) subcutaneously in the morning 5 days per week for 4 weeks. Discard any remaining medication.

A sample week

  1. M
  2. T
  3. W
  4. T
  5. F
  6. S
  7. S

5 days a week

The science of neuro peptides

Semax enhances cerebral blood flow, dopamine signaling, and cognitive performance in Russian trials. Selank reduces anxiety and supports mood via anxiolytic peptide pathways.

Western clinical data are limited but growing. Your physician uses these based on the extensive evidence from Eastern European research and emerging US interest. Close monitoring during the first month helps establish your response.

Learn more

Important safety information and common side effects

Neuro peptides are prescribed off-label based on preclinical and early clinical evidence. Common mild effects include injection-site reactions, headache, or temporary sleep changes in the first week. DSIP, Semax, and Selank are not prescribed during pregnancy or breastfeeding, or with active psychiatric medication without careful discussion—some combinations require monitoring or dose adjustment. Tell your physician about every medication, supplement, and any history of seizures or psychosis. Stop and seek care for severe headache, agitation, mood changes that interfere with daily life, or signs of allergic reaction.

Every plan includes

  • Personalized, physician-guided plan
  • Monthly, 3-month and 6-month plans
  • Dispensed by a US-licensed compounding pharmacy
  • Unlimited protocol adjustments and messaging
  • Ongoing support and check-ins
  • Pause or cancel anytime
  • Reviewed by our in-house physicians
Get Started

How it works

  1. 1.Connect with a physician

    Answer a few questions online and a US-licensed physician reviews your health, history and goals to make sure treatment is right for you. 100% online. No in-person visit required.

  2. 2.Get your discreet shipment

    If approved, your treatment is compounded by a US-licensed, LegitScript-certified pharmacy, inspected for quality, and shipped discreetly to your door.

  3. 3.Receive continuous support

    Start with one goal, then keep building over time. Unlimited physician messaging, easy refills and dose adjustments, all from the Zepym Health app.

Semax + Selank educational content reviewed by our physician

Scott Nass, MDDoctor of Medicine, board-certified in Family Medicine

Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.

Frequently asked questions

How do I use Semax / Selank?

Injected under the skin, 5 days a week, in the morning. The starting prescription is 20 units (0.2 mg) each time. Your physician sets your own dose and it is printed on your label.

What exactly is in it?

Semax, Selank.

How much arrives in each shipment?

1 vial at the starting strength, shipped to your door from a licensed US pharmacy.

Why are these from Eastern Europe, not the US?

Semax and Selank were developed and extensively studied in Russia and Eastern Europe starting in the 1990s. They have decades of clinical use there. Western research and FDA trials are far newer. Your physician weighs the geographic evidence when deciding if these fit your goals.

Why are these off-label?

Off-label means not FDA-approved for these uses, but prescribed by physicians based on preclinical research and clinical experience. It is common in medical practice, especially for emerging therapies. Your physician explains what is known and what remains uncertain.

Can I combine these with other medications?

Tell your physician about every medication, especially psychiatric drugs (SSRIs, antipsychotics), stimulants, or sleep aids. Some combinations need careful timing, dose adjustment, or extra monitoring. Do not start or stop any other medications without discussing with your physician.

What if I don't notice a change?

Some people respond quickly; others take 4–8 weeks. Keep a detailed sleep or mood journal to spot subtle changes. If no response after 6–8 weeks, your physician may adjust the dose, try a different peptide, or explore other options.

Are these safe long-term?

Long-term safety data are limited because human use is recent. Your physician monitors you regularly and reassesses the plan every 3–6 months. If any concerning symptoms arise, stop immediately and report them.

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The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Individual results vary.

Sources

  1. 1

    Delta sleep-inducing peptide (DSIP): a review of its effects on sleep.

    Sleep Med Rev, 2003
  2. 2

    Semax: a novel neuropeptide candidate for cognitive enhancement and neuroprotection.

    Ann NY Acad Sci, 2005

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