Hormone care that
meets you where you are
Hormones shape sleep, mood, energy, bone and body composition. When they shift, the right therapy, at the right dose, prescribed and followed by a licensed physician, can put the ground back under your feet.
Rated 4.9/5 by our members
Products
Physician-prescribed hormone therapy
Estradiol cypionate for women in menopause or perimenopause and for gender-affirming care; gonadorelin for men who want to preserve their own testosterone signal, especially on testosterone therapy.
Rated 4.9/5 by our members
Symptoms have causes, and causes have treatments
Hot flashes, broken sleep, low mood, brain fog, joint aches: for many women these are the sound of estrogen falling. For men on testosterone therapy, a shrinking signal from the brain to the testes is what quietly costs fertility and testicular volume.
Both have well-studied treatments. What matters is the right candidate, the right dose and a physician who follows you.
Find Your Treatment
Estradiol
Hormone therapy is the most effective treatment for hot flashes and night sweats, and it protects bone. For healthy women under 60 or within 10 years of menopause, the benefits generally outweigh the risks.
Gonadorelin
Gonadorelin is a copy of the brain's own GnRH signal. Given in small pulses it keeps the testes stimulated, which is why it is used alongside testosterone therapy and in fertility care.
Followed, not just prescribed
Hormones are adjusted, not set. Your physician reviews symptoms and, when useful, lab work at each check-in and changes the dose with you.
Disclaimer
Individual results vary. Statements about menopausal hormone therapy reflect the 2022 position statement of The North American Menopause Society; compounded estradiol and gonadorelin are not the FDA-approved brand-name products.
What to expect, month by month
Day 1
A licensed physician reviews your history and, when needed, asks for labs before deciding on therapy and a starting dose.
Weeks 2–4
Estradiol: hot flashes and night sweats often ease within the first weeks. Gonadorelin: the pulsed signal starts reaching the testes.
3 Months
Your physician reviews symptoms and any labs and adjusts the dose. Sleep, mood and energy usually settle by now.
6 Months
A stable dose. For gonadorelin on testosterone therapy, this is when preserved testicular volume and fertility markers are typically reassessed.
1 Year and Beyond
Ongoing therapy is reviewed at least yearly: the goal is the lowest dose that keeps you well, for as long as it makes sense for you.
Disclaimer
The above statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Estrogen therapy carries a boxed warning: see the important safety information before starting.
Dive deeper
Hormone care, guided by physicians
Every plan is prescribed and adjusted by a US-licensed physician, and compounded to order by pharmacies that test every batch.
Every plan is reviewed by a licensed physician
Nothing is prescribed until a US-licensed physician has reviewed your health, history and goals, and your dose is adjusted with you at check-ins.
Compounded in the US, tested for purity and potency
We only work with US-licensed, LegitScript-certified pharmacies that compound to USP standards and lab-test every batch.
Who hormone therapy is for, and who it isn't
Estrogen is not for everyone: a history of breast or uterine cancer, blood clots, stroke or unexplained bleeding rules it out, and the balance of benefit and risk changes with age and time since menopause.
That is exactly why it is prescribed after a real review of your history, not sold off a shelf. If it isn't right for you, your physician says so and helps you find what is.
Find Your TreatmentCutting-edge science, doable by all
We make cutting-edge science accessible, personal, and practically clear, so anyone can benefit from a longer, healthier life.
Meet our physicians
- Personalized doses tailored to your biology
- Compounded by US-licensed pharmacies
- Expert, human guidance from a physician who cares
What to expect with Zepym Health
- 1
Find your solution
- 2
Complete a review with a licensed physician
- 3
Receive your discreet delivery
- 4
Get ongoing, personalized support
Feel like yourself again
Answer a few questions and a licensed physician will decide whether hormone therapy fits your history and goals, and at what dose.
Find Your TreatmentEvery plan includes
- Physician review before anything is prescribed
- US-licensed compounding pharmacy
- Unlimited physician messaging
- Free, discreet shipping
- Pause or cancel anytime
Hormone therapy educational content medically reviewed by our physician
Scott Nass, MD
Doctor of Medicine, board-certified in Family Medicine
Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.
Frequently asked questions
Backed by
the research.
We read the research so you don't have to. Here's what the science says.
Disclaimer
Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Benefits outlined are based on third-party studies. Individual results vary.