Everything you wanted to ask — answered.

GLP-1 receptor agonists (like semaglutide and tirzepatide) are prescription medications that help regulate appetite, slow gastric emptying, and improve insulin sensitivity. Combined with lifestyle changes, they support sustainable weight loss under medical supervision.

Injections are taken once weekly and are well-suited for patients comfortable with self-administration. Tablets are an oral, needle-free option for those who prefer to avoid injections. Your clinician will recommend the best fit for you during your consultation based on your medical history and preferences.

Many patients notice reduced appetite within the first few weeks, with weight loss building gradually over months. In published clinical research, adults taking semaglutide 2.4 mg lost an average of 16.9% of their body weight over 68 weeks (STEP-1 trial, New England Journal of Medicine, 2021). Trials studied branded products; compounded formulations are not FDA-approved. Individual responses vary and no outcome is guaranteed — your clinician monitors your progress and adjusts your dose over time.

Semaglutide activates one hormone receptor (GLP-1), while tirzepatide activates two (GLP-1 and GIP). In clinical trials, adults taking semaglutide 2.4 mg lost an average of 16.9% of body weight over 68 weeks (STEP-1, NEJM 2021), and adults taking tirzepatide 15 mg lost an average of 22.5% over 72 weeks (SURMOUNT-1, NEJM 2022). Trials studied branded products; compounded formulations are not FDA-approved. Individual results vary — your clinician will recommend the option that best fits your medical history and goals.

The consultation fee for your initial medical review is shown at checkout before you pay. Completing the intake does not obligate you to start treatment, and you are not charged for medication unless a clinician prescribes it and you choose to begin.

A licensed, board-certified physician licensed in your state reviews your intake and medical history. Prescription decisions are made independently by your clinician based on clinical eligibility.

Yes. Ongoing care is included — secure messaging with your care team, follow-ups, and dose adjustments are all part of your subscription.

The online health assessment is completed at your own pace and then reviewed by a licensed provider. If prescribed, your medication ships from a licensed pharmacy: once shipped, refrigerated medications arrive the next day and everything else within 2 days.

No. We are a cash-pay practice and don't bill insurance. Each treatment page shows its current price; longer plans cost less per month.

Each treatment page shows its current monthly price, with no insurance needed. The price includes the physician review, your prescription if approved, the medication, discreet shipping and ongoing support from your care team, and longer plans cost less per month. For comparison, brand-name GLP-1 medications can list for over $1,000 per month without insurance in the U.S.

Many patients use HSA or FSA cards at checkout. Eligibility depends on your plan administrator's rules — we recommend confirming before purchase.

Yes. You can pause or cancel your plan from your account dashboard at any time, no questions asked.

Like all medications, GLP-1s can have side effects (most commonly nausea, especially during the first weeks). Your clinician will discuss these in detail and adjust your dose to minimize them. See our Medical Disclaimer for full risk information.

No. Compounded medications are not FDA-approved, and the FDA does not verify the safety, effectiveness, or quality of compounded drugs before they are marketed. A compounded medication is only prescribed when a licensed clinician determines it is medically appropriate for you. Your clinician will discuss the risks and benefits, monitor your response, and review your medical history. See our Medical Disclaimer for full information.

Yes. Licensed U.S. pharmacies may prepare compounded medications for an individual patient under a valid prescription, in accordance with federal law (Sections 503A/503B of the Food, Drug & Cosmetic Act) and state pharmacy regulations. Compounded medications are not FDA-approved. Zepym Health works only with state-licensed U.S. pharmacies.

Medications ship directly from a licensed pharmacy to your home in discreet, temperature-controlled packaging. Once shipped, refrigerated medications arrive the next day and everything else within 2 days.

We serve patients across the U.S. Whether a treatment is available in your state is confirmed during your intake, based on your state of residence; some medications vary with each state's pharmacy rules.

Care is provided through ZMD of CA, P.C., our affiliated medical practice. Our medical director is Scott Nass, MD, board-certified in Family Medicine. Your plan is always reviewed by a physician licensed in the state where you live.

Your medication is prepared by a state-licensed U.S. pharmacy in our network. Which one depends on the medication you are prescribed, and your care team can tell you at any time.

Certain medications, formulations, or fulfillment options may vary depending on state-specific pharmacy regulations, prescribing requirements, and dispensing restrictions.