Zepym Health

Skin

Clearer, brighter skin, with a prescription.

Tretinoin, acne, brightening and peptide formulas compounded for your skin, prescribed by a licensed physician and shipped to your door.

Find your treatment
  • Board-certified doctors
  • Licensed U.S. pharmacies
  • 100% online
  • Free, discreet shipping

Every skin treatment, in one place.

Real products and real prices from our pharmacy. Your physician helps you choose the formula and the strength.

Cream

Tretinoin Cream

Topical retinoid cream for wrinkles, acne, and photoaging. Prescription-strength skin renewal.

Starting at $129/mo

  • Cream

    Acne Cream with Tretinoin

    Acne treatment combining antibiotics (clindamycin/erythromycin/ketoconazole) with tretinoin for faster clearance and post-acne healing.

    Starting at $139/mo

  • Cream

    Hydroquinone / Tretinoin / Hydrocortisone Cream

    Classic Kligman formulation combining depigmenting, retinoid, and anti-inflammatory agents. Gold standard for melasma.

    Starting at $129/mo

  • Injection

    GHK-Cu

    A naturally occurring copper peptide studied for skin repair, firmness and healthy aging. Prescribed and dosed by a licensed physician.

    Starting at $209/mo

  • Injection

    GHK-Cu / Epithalon

    GHK-Cu for skin and tissue repair paired with Epithalon for cellular aging, in one longevity-focused vial. Prescribed and dosed by a licensed physician.

    Starting at $229/mo

  • Cream

    Acne Cream

    Triple-action topical for acne: antibiotic (clindamycin + erythromycin) and antifungal (ketoconazole). Covers bacterial and fungal acne.

    Starting at $139/mo

  • Cream

    Brightening Cream

    Stronger prescription cream for stubborn melasma and dark spots: hydroquinone 6% with tretinoin, hydrocortisone, kojic acid and vitamins C and E. A short course, usually up to 8 weeks.

    Starting at $149/mo

  • Cream

    Clarity Cream

    Acne and post-acne formula combining azelaic acid, niacinamide, clindamycin, and tretinoin. Anti-inflammatory and cell-renewing.

    Starting at $149/mo

  • Cream

    ClearTone Cream

    Brightening and anti-inflammatory cream combining azelaic acid, hydroquinone, kojic acid, tranexamic acid, and niacinamide. For post-acne hyperpigmentation.

    Starting at $149/mo

  • Capsule

    Doxycycline

    Oral antibiotic (tetracycline) for acne and rosacea at low anti-inflammatory doses. Available as capsules and tablets.

    Starting at $99/mo

See all 22 treatments

Prescription strength, used the right way.

Topical retinoids like tretinoin are a first-line treatment for acne and the best-studied topical for sun-damaged skin. Hydroquinone is a standard treatment for dark spots and melasma.

They work, but they ask for patience and care: the first weeks can bring dryness and peeling, and daily sunscreen is part of the treatment.

See the treatments

What you can expect

  • Fewer breakouts

    Retinoids clear clogged pores and help prevent new ones; it takes about two to three months.

  • Smoother texture

    Fine lines and rough texture improve gradually with months of steady use.

  • More even tone

    Brightening formulas fade dark spots over weeks to months, alongside sunscreen.

  • Adjusted to your skin

    Your physician starts low and adjusts the strength as your skin adapts.

Individual results vary. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate.

How prescription skin care works

  1. Step 1

    Day 1

    Answer a few questions and share photos of your skin. A licensed physician reviews them.

  2. Step 2

    Weeks 1–4

    Start slowly, a few nights a week. Dryness and peeling are common as skin adjusts.

  3. Step 3

    Months 2–3

    Breakouts calm and tone starts to even out. Your physician can adjust the strength.

  4. Step 4

    Ongoing

    Keep going to keep the results, with daily sunscreen and messaging with your care team.

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The science

How tretinoin works

Tretinoin speeds up how skin cells turn over and keeps pores from clogging. Over months it also builds new collagen, which is why it softens fine lines.

It makes skin more sensitive to the sun and is not used during pregnancy. Your physician picks the strength and tells you how to start.

Find your treatment
How long until I see results?

Acne usually improves in two to three months; fine lines and tone take longer. The first weeks can look worse before they look better.

Is peeling normal?

Yes. Dryness, redness and peeling are common in the first weeks. Using it a few nights a week at first and a gentle moisturizer helps.

Can I use it while pregnant?

Topical retinoids are not used during pregnancy. Tell your physician if you are pregnant, planning to be or breastfeeding.

Do I need sunscreen?

Yes, every day. Retinoids and brightening creams make skin more sensitive to the sun, and the sun undoes their work on dark spots.

How is it billed?

Monthly, every 3 months or every 6 months; longer plans cost less per month. Shipping is free and you can pause or cancel anytime.

Start your skin plan today.

Answer a few questions online. A licensed physician reviews them and, if it's right for you, your treatment ships to your door.

  • Physician review before anything is prescribed
  • US-licensed compounding pharmacy
  • Unlimited messaging with your care team
  • Free, discreet shipping
  • Pause or cancel anytime
Get started

From $69/mo

Skin care content medically reviewed by our physician

Scott Nass, MD Doctor of Medicine, board-certified in Family Medicine

Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.

References

1Guidelines of care for the management of acne vulgaris (American Academy of Dermatology).J Am Acad Dermatol, 2024 (Reynolds RV et al.)

Compounded medications are not FDA-approved and the FDA has not reviewed them for safety, efficacy, or quality. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Individual results vary.