Semaglutide + B12
RxA physician-guided semaglutide plan designed to support appetite regulation, metabolic health, and long-term care beyond the scale, with vitamin B12 for energy.
- Supports the gut-brain signals that help regulate fullness
- Once-weekly GLP-1 injection, dosed and adjusted by your physician
- Paired with vitamin B12 to support energy while you lose weight
- Monthly, 3-month and 6-month plans
- Starting price applies to the 6-month plan
- US-licensed pharmacies
- Pause or cancel anytime
Starting at
$189 / mo
- Physician-guided care
- Ongoing, expert support
- 100% online
- Free, discreet shipping
Disclaimer
Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Compounded medications are not the FDA-approved brand-name products.
What is Semaglutide?
(sem-a-GLOO-tide, a GLP-1 receptor agonist)
Your body makes GLP-1 after you eat. It is one of the signals that tells the brain “we've had enough,” while slowing digestion and steadying blood sugar after meals. Semaglutide mimics that hormone, keeping the fullness signal active longer to support appetite regulation, steadier eating and metabolic health.
Get StartedAverage body weight reduction in the pivotal clinical trial of brand-name semaglutide
~15%
In the pivotal STEP 1 trial, adults with obesity lost on average about 15% of body weight over 68 weeks with once-weekly brand-name semaglutide plus lifestyle changes. Compounded semaglutide is not the brand-name product and was not studied in that trial; individual results vary.
How GLP-1 care works
Day 1
A US-licensed physician reviews your health profile, goals and treatment history and sets your starting dose.
7 Days
Your first weekly injection. Appetite usually quiets within days; some nausea in the first weeks is common and fades as the dose settles.
30 Days
Fullness comes sooner and cravings soften. Your physician checks how you feel before any dose increase.
6 Months
Weight loss builds steadily with the plan, food and movement. Doses are adjusted at your check-ins.
1 Year and Beyond
Maintenance is part of the plan: your physician decides with you how to hold your results or taper.
Results you can feel
Better feelingBetter bodyWeight loss
steady and sustained, with your physician adjusting the dose
Appetite regulation
the most common change members report in their first weeks
Metabolic health
steadier blood sugar after meals
Energy
vitamin B12 helps offset the fatigue that can come with eating less
Individual results vary. Benefits reflect what Zepym Health members commonly report to their physician at check-ins; they are not the results of a clinical trial.
Is semaglutide right for you?
GLP-1 medications are prescribed based on your BMI, your health history and your goals. Find your BMI on the chart to see whether you're within the usual range for treatment, then let your physician decide.
This chart is not a medical diagnosis. Your physician approves or declines a prescription at their discretion after reviewing your unique health profile; approval is not guaranteed by these criteria.
| BMI | Is semaglutide right for me? |
|---|---|
| 24.9 or less | No |
| 25.0 to 29.9 | Case-by-case (with a weight-related condition) |
| 30.0 or above | Likely |
Physician-guided semaglutide, done right
Not all GLP-1 care is created equal. Ours is prescribed by US-licensed physicians and compounded to order by LegitScript-certified US pharmacies, with your dose adjusted at every check-in and one flat price at every dose.
- US-licensed physicians evaluate every prescription individually
- Dose changes at your check-ins, with no upcharge as your dose goes up
- Compounded and tested to USP standards by LegitScript-certified pharmacies
Your plan, reviewed
Physician-reviewedDose set by a physician, adjusted at every check-in
Your reviewing physician
Scott Nass, MD
Board-certified family physician. Every semaglutide plan at Zepym Health is reviewed by a licensed physician before anything is prescribed, and adjusted with you as you go.
Meet the teamClinically studied
The science of semaglutide
GLP-1 is a hormone the body already makes after eating, telling the brain “we've had enough” while slowing digestion and steadying blood sugar. Semaglutide amplifies that same signal for a full week per dose.
In the pivotal STEP 1 trial, adults with obesity lost on average about 15% of body weight over 68 weeks with once-weekly brand-name semaglutide plus lifestyle changes. In people with obesity but without diabetes, brand-name semaglutide also reduced major cardiovascular events in the SELECT trial. Compounded versions are prescribed by your physician when appropriate and are not the brand-name products.
Learn more
Subscribe & save
Weight care that starts with you
One flat price at every dose, with your physician's care included. Longer plans cost less per month.
$189/ mo
Applies to the 6-month plan billed in full ($189/mo on the monthly plan)
What's included
- Personalized, physician-guided plan
- Monthly, 3-month and 6-month plans
- Same price at every dose, no dose upcharges
- Dispensed by a US-licensed compounding pharmacy
- Unlimited dose adjustments and messaging
- Ongoing support and check-ins
- Pause or cancel anytime
Personalized for you
Made for your biology
No two people lose weight the same way, so no two plans are exactly the same. Your plan is guided by your BMI, your history, your response and your priorities, dose by dose.
Get StartedHow it works
Choosing how you age starts here
- 1
Physician-led
Connect with a physician
Answer a few questions online and a US-licensed physician reviews your health, history and goals to make sure treatment is right for you. 100% online. No in-person visit required.
2Fast, discreet shipping
Get your discreet shipment
If approved, your treatment is compounded by a US-licensed, LegitScript-certified pharmacy, inspected for quality, and shipped discreetly to your door.
3100% online
Receive continuous support
Start with one goal, then keep building over time. Unlimited physician messaging, easy refills and dose adjustments, all from the Zepym Health app.
Disclaimer
The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Individual results vary.
Semaglutide + B12 educational content reviewed by our physician
Scott Nass, MD
Doctor of Medicine, board-certified in Family Medicine
Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.
Frequently asked questions
May the source be with you.
We read the research so you don't have to. Here's what the science says.
- 1
Once-weekly semaglutide 2.4 mg produced a mean weight loss of about 15% over 68 weeks in adults with overweight or obesity (STEP 1).
New England Journal of Medicine, 2021 (Wilding JPH et al.) - 2
Semaglutide reduced major adverse cardiovascular events in adults with overweight or obesity without diabetes (SELECT).
New England Journal of Medicine, 2023 (Lincoff AM et al.) - 3
Mechanisms of GLP-1: appetite, gastric emptying and glucose regulation.
Cell Metabolism, 2018 (Drucker DJ)
Starting at $189 / mo
Get Started