Explore thyroid treatments
built around the test that finds the problem.

Tiredness, weight changes and feeling cold have many causes. Physician-led care confirms hypothyroidism with a blood test, starts with the standard medicine, and rechecks your dose.

Thyroid symptoms need a test
before they need a prescription.

Hypothyroidism is treated with levothyroxine as the standard of care, and it is confirmed with a blood test.¹ Tiredness and low mood also have other causes. In adults aged 65 and older with subclinical hypothyroidism, a year of levothyroxine did not improve symptoms compared with placebo.²

Our in-house team of U.S.-licensed physicians and nurse practitioners checks your TSH, treats what your labs confirm, and rechecks your dose as you go.

  1. 1.Guidelines for the Treatment of Hypothyroidism: prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement, Jonklaas J et al., Thyroid, 2014.
  2. 2.Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism (TRUST), Stott DJ et al., N Engl J Med, 2017.

What changes with the thyroid
and what does not.

  • No benefit in older adults737 adults

    On levothyroxine, the hypothyroid symptom score did not differ from placebo after one year (between-group difference 0.0 points, 95% CI -2.0 to 2.1) in 737 adults aged 65 and older with subclinical hypothyroidism.

    Stott DJ et al., N Engl J Med, 2017
  • Preferred desiccated thyroid48.6%

    of 70 adults with hypothyroidism preferred desiccated thyroid after 16 weeks on each product; 18.6% preferred levothyroxine and 32.9% had no preference. Symptom and neurocognitive measures did not differ between the two.

    Hoang TD et al., J Clin Endocrinol Metab, 2013
  • Same TSH on T3 and desiccated22 weeks

    on levothyroxine alone, levothyroxine plus liothyronine, or desiccated thyroid, in 75 adults: TSH stayed in range in all three arms, and primary and secondary outcomes did not differ, except a small rise in heart rate on desiccated thyroid.

    Shakir MKM et al., J Clin Endocrinol Metab, 2021

In the 2014 ATA guideline review, no alternative preparation was shown to be consistently better than levothyroxine alone for health outcomes. Jonklaas J et al., Thyroid, 2014

Trial results are averages for specific products, doses and groups, and they are not predictions for you. The desiccated thyroid and T3 studies were small crossover trials, and patient preference was one of their outcomes. The TRUST result applies to adults aged 65 and older with subclinical hypothyroidism, not to people already diagnosed and treated. Compounded products are not FDA-approved, and these trials did not test them.

The right thyroid plan
starts with a TSH test.

When you have symptoms that could come from your thyroid, you should not have to guess. Our care team checks your TSH and your history, starts with the standard medicine, and adjusts the dose when your labs say so.

We test first, we start with levothyroxine as the standard, and we recheck TSH after every dose change, so you know what changed and why, with plans starting at $79 a month.

Start here

We read the research on thyroid
before we prescribe it.

Thyroid care has clear guidelines, and it also attracts a lot of marketing for alternatives. We read the trials, state their limits, and keep the treatments the evidence supports.

Every thyroid treatment,
in one place.

Real products and real prices from our pharmacy. Your physician helps you choose the medicine, the form and the dose.

Tablets

1

Taken by mouth with water.

  • Tablet

    Armour Thyroid

    Armour Thyroid, a desiccated thyroid extract used to treat hypothyroidism. Commercial formulation prescribed and dosed by a licensed physician.

    30 tablets per month

    Starting at $129/mo

Capsules

3

Taken by mouth with water.

  • Capsule

    T3 / T4 Capsules

    Combination of T3 (Liothyronine) and T4 (Thyroxine) in slow-release capsules for comprehensive thyroid hormone replacement. Prescribed and dosed by a licensed physician.

    30 capsules per month

    Starting at $79/mo

  • Capsule

    Thyroxine (T4) Capsules

    Thyroxine (T4) slow-release capsules for thyroid hormone replacement therapy. Prescribed and dosed by a licensed physician.

    30 capsules per month

    Starting at $79/mo

  • Capsule

    Liothyronine (T3) Capsules

    Liothyronine (T3) slow-release capsules, used to support thyroid hormone levels and metabolic function. Prescribed and dosed by a licensed physician.

    30 capsules per month

    Starting at $89/mo

4 treatments in this area, all from our live catalog.

Questions,
answered.

Contact support
Can thyroid hormone help me lose weight?

No. Thyroid hormone is not a weight-loss treatment, and we do not prescribe it for that purpose. In the desiccated thyroid trial, participants lost about 3 lb, a small change that is not a reason to take it.

Are these products FDA-approved?

No. Compounded medications are not FDA-approved, and desiccated thyroid products are not FDA-approved either. The trials we cite tested specific products and doses, not every product we sell.

When will you recheck my TSH?

About six to eight weeks after any dose change, because levothyroxine takes weeks to settle in the blood. Your physician reviews the result before changing the dose again.

Will you treat a borderline TSH if I have no symptoms?

Not on the number alone. In the TRUST trial of adults 65 and older with subclinical hypothyroidism, levothyroxine did not improve symptoms over one year, so we weigh the result together with your history.

Can I add T3 or switch to desiccated thyroid?

We discuss it with you. Some symptomatic patients preferred T3 or desiccated thyroid in trials, but overall outcomes were similar, so we start with levothyroxine and decide any change with labs and symptoms.

References

  1. 1.Guidelines for the Treatment of Hypothyroidism: prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement Thyroid, 2014 (Jonklaas J et al.)
  2. 2.Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism (TRUST) N Engl J Med, 2017 (Stott DJ et al.)
  3. 3.Desiccated thyroid extract compared with levothyroxine in the treatment of hypothyroidism: a randomized, double-blind, crossover study J Clin Endocrinol Metab, 2013 (Hoang TD et al.)
  4. 4.Comparative Effectiveness of Levothyroxine, Desiccated Thyroid Extract, and Levothyroxine+Liothyronine in Hypothyroidism J Clin Endocrinol Metab, 2021 (Shakir MKM et al.)

Compounded medications are not FDA-approved and the FDA has not reviewed them for safety, efficacy, or quality. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Trial results describe groups, not individual outcomes. Individual results vary.