Tirzepatide + B12
RxA physician-guided tirzepatide plan designed to support appetite regulation, metabolic health, and long-term care beyond the scale, with vitamin B12 for energy.
- Supports the gut-brain signals that help regulate fullness
- Once-weekly dual GLP-1/GIP injection, dosed and adjusted by your physician
- Paired with vitamin B12 to support energy while you lose weight
- Monthly, 3-month and 6-month plans
- Starting price applies to the 6-month plan
- US-licensed pharmacies
- Pause or cancel anytime
Starting at
$189 / mo
- Physician-guided care
- Ongoing, expert support
- 100% online
- Free, discreet shipping
Disclaimer
Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Compounded medications are not the FDA-approved brand-name products.
What is Tirzepatide?
(tir-ZEP-a-tide, a dual GLP-1 / GIP receptor agonist)
Your body makes GLP-1 and GIP after you eat. They are the signals that tell the brain “we've had enough,” slow digestion and steady blood sugar. Tirzepatide mimics both hormones at once, which is why it produced the largest weight loss seen in clinical trials of this class.
Get StartedAverage body weight reduction in the pivotal clinical trial of brand-name tirzepatide
up to 21%
In the pivotal SURMOUNT-1 trial, adults with obesity lost up to about 21% of body weight over 72 weeks with once-weekly brand-name tirzepatide plus lifestyle changes. Compounded tirzepatide is not the brand-name product and was not studied in that trial; individual results vary.
How GLP-1 care works
Day 1
A US-licensed physician reviews your health profile, goals and treatment history and sets your starting dose.
7 Days
Your first weekly injection. Appetite usually quiets within days; some nausea in the first weeks is common and fades as the dose settles.
30 Days
Fullness comes sooner and cravings soften. Your physician checks how you feel before any dose increase.
6 Months
Weight loss builds steadily with the plan, food and movement. Doses are adjusted at your check-ins.
1 Year and Beyond
Maintenance is part of the plan: your physician decides with you how to hold your results or taper.
Results you can feel
Better feelingBetter bodyWeight loss
steady and sustained, with your physician adjusting the dose
Appetite regulation
the most common change members report in their first weeks
Metabolic health
steadier blood sugar after meals
Energy
vitamin B12 helps offset the fatigue that can come with eating less
Individual results vary. Benefits reflect what Zepym Health members commonly report to their physician at check-ins; they are not the results of a clinical trial.
Is tirzepatide right for you?
GLP-1 medications are prescribed based on your BMI, your health history and your goals. Find your BMI on the chart to see whether you're within the usual range for treatment, then let your physician decide.
This chart is not a medical diagnosis. Your physician approves or declines a prescription at their discretion after reviewing your unique health profile; approval is not guaranteed by these criteria.
| BMI | Is tirzepatide right for me? |
|---|---|
| 24.9 or less | No |
| 25.0 to 29.9 | Case-by-case (with a weight-related condition) |
| 30.0 or above | Likely |
Physician-guided tirzepatide, done right
Not all GLP-1 care is created equal. Ours is prescribed by US-licensed physicians and compounded to order by LegitScript-certified US pharmacies, with your dose adjusted at every check-in and one flat price at every dose.
- US-licensed physicians evaluate every prescription individually
- Dose changes at your check-ins, with no upcharge as your dose goes up
- Compounded and tested to USP standards by LegitScript-certified pharmacies
Your plan, reviewed
Physician-reviewedDose set by a physician, adjusted at every check-in
Your reviewing physician
Scott Nass, MD
Board-certified family physician. Every tirzepatide plan at Zepym Health is reviewed by a licensed physician before anything is prescribed, and adjusted with you as you go.
Meet the teamClinically studied
The science of tirzepatide
GLP-1 and GIP are hormones the body makes after eating, telling the brain “we've had enough” while slowing digestion and steadying blood sugar. Tirzepatide amplifies both signals at once for a full week per dose.
In the pivotal SURMOUNT-1 trial, adults with obesity lost up to about 21% of body weight over 72 weeks with once-weekly brand-name tirzepatide plus lifestyle changes. In people with obesity but without diabetes, brand-name semaglutide also reduced major cardiovascular events in the SELECT trial. Compounded versions are prescribed by your physician when appropriate and are not the brand-name products.
Learn more
Subscribe & save
Weight care that starts with you
One flat price at every dose, with your physician's care included. Longer plans cost less per month.
$189/ mo
Applies to the 6-month plan billed in full ($189/mo on the monthly plan)
What's included
- Personalized, physician-guided plan
- Monthly, 3-month and 6-month plans
- Same price at every dose, no dose upcharges
- Dispensed by a US-licensed compounding pharmacy
- Unlimited dose adjustments and messaging
- Ongoing support and check-ins
- Pause or cancel anytime
Personalized for you
Made for your biology
No two people lose weight the same way, so no two plans are exactly the same. Your plan is guided by your BMI, your history, your response and your priorities, dose by dose.
Get StartedHow it works
Choosing how you age starts here
- 1
Physician-led
Connect with a physician
Answer a few questions online and a US-licensed physician reviews your health, history and goals to make sure treatment is right for you. 100% online. No in-person visit required.
2Fast, discreet shipping
Get your discreet shipment
If approved, your treatment is compounded by a US-licensed, LegitScript-certified pharmacy, inspected for quality, and shipped discreetly to your door.
3100% online
Receive continuous support
Start with one goal, then keep building over time. Unlimited physician messaging, easy refills and dose adjustments, all from the Zepym Health app.
Disclaimer
The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Individual results vary.
Tirzepatide + B12 educational content reviewed by our physician
Scott Nass, MD
Doctor of Medicine, board-certified in Family Medicine
Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.
Frequently asked questions
May the source be with you.
We read the research so you don't have to. Here's what the science says.
- 1
Once-weekly tirzepatide produced mean weight loss of up to about 21% over 72 weeks in adults with obesity (SURMOUNT-1).
New England Journal of Medicine, 2022 (Jastreboff AM et al.) - 2
Semaglutide reduced major adverse cardiovascular events in adults with overweight or obesity without diabetes (SELECT), evidence of the class's metabolic benefits.
New England Journal of Medicine, 2023 (Lincoff AM et al.) - 3
Mechanisms of GLP-1 and incretin hormones: appetite, gastric emptying and glucose regulation.
Cell Metabolism, 2018 (Drucker DJ)
Starting at $189 / mo
Get Started