Armour Thyroid
Armour Thyroid, a desiccated thyroid extract used to treat hypothyroidism. Commercial formulation prescribed and dosed by a licensed physician.
Tablet
from $119/mo
Taken by mouth · Once a day
ThyroidCombinationOptimization
T3 + T4 Combination Capsules
Compounded T3 and T4 in one capsule at a ratio your physician sets. Combines the reserve benefit of T4 with the immediate activity of T3. Oral, once or twice daily.
- T4 and T3 together at a custom ratio set by your physician
- Faster onset than T4 alone, more stable than T3 alone
- Dosed as few or many capsules as your protocol needs
- Monthly$99/mo
- Every 3 months$237 billed up front$79/mo
- Every 6 monthsBest value$414 billed up front$69/mo
- Free, discreet shipping
- Licensed U.S. pharmacy
- Board-certified physicians
Disclaimer: Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Compounded medications are not FDA-approved brand-name products.
- How
- Taken by mouth
- How often
- Once a day
- Each shipment
- 30 capsules
- Strengths
- 7 options · 4.5–27 mcg / 114 mcg
What is a T3 + T4 combination?
(compounded thyroid replacement)
Some people thrive on T4 alone; others feel better with some T3 upfront. A T3/T4 combination gives you both: T4 as a stable reserve, and T3 for immediate activity. Your physician sets the ratio based on your symptoms, labs, and response. A common ratio is 4:1 or 5:1 T4 to T3, but yours will be individualized.
What's in it
- Liothyronine (T3)Thyroid hormone replacement
- Thyroxine (T4)Thyroid hormone replacement
Customized
T4/T3 ratio compounded by a licensed pharmacy
The combination works for people who need more immediate T3 activity than T4 alone provides, but don't tolerate T3-only dosing. Ratio is adjusted at every check-in.
Is it right for you?
Who it's for
People who want T4 and T3 in a ratio set by their physician.
What sets it apart
Synthetic T4 and T3 in one capsule, without animal thyroid.
Worth knowing before you start
TSH is rechecked six to eight weeks after any change.
What to expect
More energy
fatigue lifts as thyroid levels normalize
Better sleep quality
mood and sleep rhythm often improve together
Mental clarity
brain fog clears; focus and concentration return
Body temperature
cold intolerance eases as metabolism normalizes
How thyroid hormones work
Day 1
A US-licensed physician reviews your thyroid symptoms (fatigue, cold intolerance, weight, mood), medical history, and medications. Discusses how thyroid hormones work and the importance of lab-guided dosing.
1Week 1
Start with an initial dose (usually conservative) of your prescribed thyroid hormone, taken once daily in the morning with water on an empty stomach.
2Weeks 4-6
Thyroid hormones accumulate slowly; effects build over 4-6 weeks. Energy, temperature regulation, and mood may shift gradually. Keep a symptom journal.
3Week 6-8
First lab check: TSH and Free T4 (or Free T3 if on T3). Your physician adjusts dose if needed. Repeat this cycle every 6-8 weeks until TSH and symptoms align.
4Beyond
Thyroid hormones work best on a stable dose. Annual labs and check-ins ensure your dose stays right as your body and needs change.
5
Individual results vary. Benefits reflect what Zepym Health members commonly report to their physician at check-ins; they are not the results of a clinical trial.
How you use it
This is the starting dose the pharmacy prints on the label. Your physician sets yours and adjusts it with you.
- How
- Taken by mouth
- Dose
- 1 capsule (4.5 mcg / 19 mcg)
- How often
- Once a day
- When
- In the morning
- Each shipment
- 30 capsules
- Pharmacy label
- Take 1 capsule (4.5 mcg / 19 mcg) by mouth once daily on an empty stomach, 30 to 60 minutes before breakfast, for 30 days.
A sample week
- M
- T
- W
- T
- F
- S
- S
Once a day
Strengths the pharmacy carries
- 27 mcg / 114 mcg
- 9 mcg / 38 mcg
- 4.5 mcg / 19 mcg
- 18 mcg / 76 mcg
- 12 mcg / 38 mcg
- 25 mcg / 150 mcg
- 12 mcg / 50 mcg
The science of thyroid hormones
T4/T3 combinations bridge the gap between T4-only and T3-only therapy. T4 provides steady-state coverage; T3 covers the peak-demand times.
No clinical trial compares all T4/T3 ratios, so your physician uses experience and your feedback to dial in the best ratio for you. Adjustment takes 4-6 weeks per change.
Learn moreImportant safety information and common side effects
Thyroid hormones regulate metabolism and affect every cell. Overdosing causes tachycardia, palpitations, anxiety, insomnia, and heat intolerance; underdosing leaves fatigue and brain fog. Thyroid hormones are not for weight loss in people with normal thyroid function. Do not use if you have uncontrolled high blood pressure, active angina, or untreated adrenal insufficiency. Tell your physician about all medications, especially beta-blockers, stimulants, and any cardiac history. Stop and seek care for rapid heartbeat, chest pain, severe shortness of breath, or signs of thyroid storm (high fever, confusion, agitation).
Every plan includes
- Personalized, physician-guided plan
- Monthly, 3-month and 6-month plans
- Dispensed by a US-licensed compounding pharmacy
- Unlimited protocol adjustments and messaging
- Ongoing support and check-ins
- Pause or cancel anytime
- Reviewed by our in-house physicians
How it works
1.Connect with a physician
Answer a few questions online and a US-licensed physician reviews your health, history and goals to make sure treatment is right for you. 100% online. No in-person visit required.
2.Get your discreet shipment
If approved, your treatment is compounded by a US-licensed, LegitScript-certified pharmacy, inspected for quality, and shipped discreetly to your door.
3.Receive continuous support
Start with one goal, then keep building over time. Unlimited physician messaging, easy refills and dose adjustments, all from the Zepym Health app.
T3 + T4 combination educational content reviewed by our physician
Scott Nass, MDDoctor of Medicine, board-certified in Family Medicine
Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.
Frequently asked questions
How do I take T3 / T4 Capsules?
Taken by mouth, once a day, in the morning. The starting prescription is 1 capsule (4.5 mcg / 19 mcg) each time. Your physician sets your own dose and it is printed on your label.
What strengths does T3 / T4 Capsules come in?
The pharmacy carries 7: 4.5 mcg / 19 mcg, 9 mcg / 38 mcg, 12 mcg / 38 mcg, 12 mcg / 50 mcg, 18 mcg / 76 mcg, 25 mcg / 150 mcg, 27 mcg / 114 mcg. Your physician chooses which one you get.
What exactly is in it?
Liothyronine (T3), Thyroxine (T4).
How much arrives in each shipment?
30 capsules at the starting strength, shipped to your door from a licensed US pharmacy.
How is this different from Armour?
Armour is a fixed ratio of natural T4 and T3 from pork thyroid. A T3/T4 combination is compounded with a ratio your physician chooses and can adjust. The flexibility is the main difference; your physician can increase T3 or T4 independently based on your response.
Why can't I feel my dose immediately?
Thyroid hormones accumulate in your tissues and bloodstream over weeks. The half-life of T4 is about 7 days, so it takes 4-5 half-lives (1 month) to reach steady state. Be patient; your physician will adjust if needed at your 6-8 week check.
Will thyroid hormone help me lose weight if my thyroid is normal?
No. Thyroid hormones are not weight-loss drugs. They work only in people with low thyroid function. Overdosing a person with normal thyroid function causes dangerous side effects (tachycardia, heat intolerance) without weight loss.
Can I adjust my dose myself?
No. Thyroid dosing requires lab values (TSH, Free T4, Free T3) to be safe and effective. Too much causes palpitations and anxiety; too little leaves you fatigued. Your physician adjusts by the numbers and your symptoms, never by guessing.
Energy and clarity from a balanced thyroid.
Liothyronine (T3) Capsules
Liothyronine (T3) slow-release capsules, used to support thyroid hormone levels and metabolic function. Prescribed and dosed by a licensed physician.
Capsule
from $79/mo
Thyroxine (T4) Capsules
Thyroxine (T4) slow-release capsules for thyroid hormone replacement therapy. Prescribed and dosed by a licensed physician.
Capsule
from $69/mo
Tirzepatide + B12
A weekly dual-action GLP-1/GIP injection for meaningful weight loss and appetite control, paired with vitamin B12 for energy.
Injection
from $208/mo
The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Individual results vary.
Sources
- 1
Hypothyroidism: evidence-based diagnosis and management in adults.
N Engl J Med, 2017 - 2
Levothyroxine replacement in primary hypothyroidism: a clinical update.
J Clin Endocrinol Metab, 2012
T3 + T4 Combination Capsulesfrom $69/mo