Acne Cream
Triple-action topical for acne: antibiotic (clindamycin + erythromycin) and antifungal (ketoconazole). Covers bacterial and fungal acne.
Cream
from $139/mo
Applied to the skin · Once a day
Anti-agingCollagenPeptide
GHK-Cu Cream
GHK-Cu (copper peptide) cream: supports skin remodeling, collagen, and overall radiance. A prescription cream compounded by a licensed pharmacy, applied once daily.
- Copper peptide supports collagen remodeling
- Improves skin firmness, elasticity, and hydration
- No irritation; use daily indefinitely
- Monthly$179/mo
- Free, discreet shipping
- Licensed U.S. pharmacy
- Board-certified physicians
Disclaimer: Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Compounded medications are not FDA-approved brand-name products.
- How
- Applied to the skin
- How often
- Once a day
- Each shipment
- 1 bottle
- Strength
- 0.5%
What is GHK-Cu cream?
(bioactive copper peptide moisturizer)
This daily moisturizer contains GHK-Cu, a natural tripeptide with copper that supports wound healing and skin remodeling. It improves skin firmness, elasticity, and hydration while supporting collagen synthesis. Unlike tretinoin or active exfoliants, GHK-Cu is non-irritating and designed for daily, long-term use as a foundational anti-aging treatment.
What's in it
- GHK-Cu CreamCopper peptide: collagen and repair
Foundational
anti-aging daily cream with no irritation or downtime
Results accumulate over 2-3 months. Use alongside active treatments (tretinoin, acids) or as standalone anti-aging therapy.
Is it right for you?
Who it's for
People who want firmer skin without a retinoid.
What sets it apart
A copper peptide cream for collagen. No hydroquinone, no tretinoin.
Worth knowing before you start
It is blue because of the copper. It can be used alongside sunscreen in the morning.
What to expect
Improved radiance
skin brightness and clarity build over weeks
No irritation
all four are gentle enough for daily use
Firmness over time
peptides and collagen support strengthen skin
Targeted benefits
LuminEye for eyes, HydroTone for hydration, etc.
How supportive skincare works
Week 1
Start with one or all four depending on your skin needs. All are gentle and safe to layer.
1Week 2–4
Skin feels more hydrated. Subtle radiance improvements. No irritation.
2Month 2–3
Fine lines appear softer. Dark circles under eyes less noticeable. Skin tone more even.
3Month 3–6+
Cumulative antioxidant and peptide benefits compound. Skin appears firmer, brighter, more resilient.
4
Individual results vary. Benefits reflect what Zepym Health members commonly report to their physician at check-ins; they are not the results of a clinical trial.
How you use it
This is the starting dose the pharmacy prints on the label. Your physician sets yours and adjusts it with you.
- How
- Applied to the skin
- Where
- affected area
- Dose
- 1 to 2 pumps
- How often
- Once a day
- When
- At bedtime
- Each shipment
- 1 bottle
- Pharmacy label
- Apply 1 to 2 pumps to the affected area at bedtime once daily, for 30 days.
A sample week
- M
- T
- W
- T
- F
- S
- S
Once a day
The science of supportive skincare
GHK-Cu stimulates collagen and elastin synthesis. Studies show improved skin firmness, elasticity and hydration with consistent 2-3 month use.
Non-irritating and suitable for all skin types, including sensitive skin and those using prescription actives.
Learn moreImportant safety information and common side effects
All four products are gentle, non-irritating, and suitable for daily use. No sun sensitivity or downtime. Safe during pregnancy after consultation. No contraindications with other treatments. Tell your physician if you have sensitivity to any ingredient (vitamin C, peptides, etc.). These are supportive skincare, not active treatments; they complement tretinoin, acids, and other prescription options. No adverse effects reported at standard doses.
Every plan includes
- Personalized, physician-guided plan
- Monthly plan
- Dispensed by a US-licensed compounding pharmacy
- Unlimited protocol adjustments and messaging
- Ongoing support and check-ins
- Pause or cancel anytime
- Reviewed by our in-house physicians
How it works
1.Connect with a physician
Answer a few questions online and a US-licensed physician reviews your health, history and goals to make sure treatment is right for you. 100% online. No in-person visit required.
2.Get your discreet shipment
If approved, your treatment is compounded by a US-licensed, LegitScript-certified pharmacy, inspected for quality, and shipped discreetly to your door.
3.Receive continuous support
Start with one goal, then keep building over time. Unlimited physician messaging, easy refills and dose adjustments, all from the Zepym Health app.
GHK-Cu cream educational content reviewed by our physician
Scott Nass, MDDoctor of Medicine, board-certified in Family Medicine
Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.
Frequently asked questions
How do I use GHK-Cu Cream?
Applied to the skin, once a day, at bedtime. The starting prescription is 1 to 2 pumps each time. Your physician sets your own dose and it is printed on your label.
How much arrives in each shipment?
1 bottle at the starting strength, shipped to your door from a licensed US pharmacy.
Can I use GHK-Cu with tretinoin?
Yes. Use tretinoin at night; GHK-Cu cream in the morning or as a base layer. They work synergistically: tretinoin accelerates cell turnover, GHK-Cu supports collagen remodeling.
Can I use all four together?
Yes. Apply in order: GHK-Cu cream + Vital C5 in morning, HydroTone as hydrating layer, LuminEye under eyes. At night, use GHK-Cu again. They layer well.
Can I use these with active treatments like tretinoin?
Yes. Use actives at night; these in morning or as base layers. They support and protect your skin while tretinoin accelerates renewal.
How long before I see results?
Immediate: improved hydration and texture. At 4-8 weeks: brightening and firmness. At 12 weeks: noticeable anti-aging benefit. Results compound.
Are these sufficient anti-aging alone?
These are maintenance and support. For significant wrinkle reduction or dark spot removal, combine with active treatments (tretinoin, hydroquinone, etc.). Alone, these prevent aging and support radiance.
Radiance built on solid support.
Acne Cream with Tretinoin
Acne treatment combining antibiotics (clindamycin/erythromycin/ketoconazole) with tretinoin for faster clearance and post-acne healing.
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Brightening Cream
Stronger prescription cream for stubborn melasma and dark spots: hydroquinone 6% with tretinoin, hydrocortisone, kojic acid and vitamins C and E. A short course, usually up to 8 weeks.
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Clarity Cream
Acne and post-acne formula combining azelaic acid, niacinamide, clindamycin, and tretinoin. Anti-inflammatory and cell-renewing.
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The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Individual results vary.
Sources
- 1
Vitamin C and antioxidant stability: mechanisms and skincare delivery.
Cosmet Dermatol, 2015 - 2
Peptides in moisturizers: collagen stimulation and barrier support.
J Cosmet Dermatol, 2019
GHK-Cu Creamfrom $179/mo