Apomorphine / Sildenafil / Tadalafil / Vardenafil Troches
Quad-mix troche combining three PDE5 inhibitors with apomorphine dopamine agonist for maximum potency and comprehensive mechanism.
Troche
from $79/mo
Dissolved under the tongue · As needed, 20–30 min before
Women's healthDesireCompounded
A berry troche with apomorphine, bremelanotide (PT-141), oxytocin and L-theanine, dissolved under the tongue 20 to 30 minutes before intimacy.
Disclaimer: Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Compounded medications are not FDA-approved brand-name products.
(desire troche)
Bremelanotide and apomorphine act on brain pathways tied to desire and arousal; oxytocin supports bonding; L-theanine is added for calm.
Vyleesi
the approved injectable form of bremelanotide for low desire in premenopausal women
This troche is a compounded, off-label combination; absorption of peptides under the tongue is variable.
Women with low desire who want something taken only when needed.
Four ingredients acting on desire in the brain, not on blood flow.
Nausea is the most common effect. Try the first one on a quiet evening.
support where it starts
better local response
less dryness and discomfort
a plan built around you
Day 1
A physician reviews your symptoms, cycle or menopause stage, medications and goals, and chooses the product.
1First uses
Use as directed; notice how your body responds and any local sensation.
2Weeks 2-4
Response becomes clearer. Daily moisturizers need a few weeks for full effect.
3Month 1
Check-in: adjust the product, add or change hormones if needed.
4Beyond
Regular reviews as your needs change.
5Individual results vary. Benefits reflect what Zepym Health members commonly report to their physician at check-ins; they are not the results of a clinical trial.
This is the starting dose the pharmacy prints on the label. Your physician sets yours and adjusts it with you.
Bremelanotide injection improved desire and reduced distress in phase 3 trials in premenopausal women with low sexual desire.
Nausea, flushing and headache are the most common effects; avoid with uncontrolled high blood pressure.
Learn moreThese products are used externally or dissolved in the mouth. Common effects are local warmth, tingling or irritation; with the desire troche, nausea, flushing and headache. Creams containing sildenafil must never be used with nitrates. Do not use during pregnancy or breastfeeding without your physician's approval. Stop and contact us if you have burning, a rash, or unusual discharge.

1.Connect with a physician
Answer a few questions online and a US-licensed physician reviews your health, history and goals to make sure treatment is right for you. 100% online. No in-person visit required.

2.Get your discreet shipment
If approved, your treatment is compounded by a US-licensed, LegitScript-certified pharmacy, inspected for quality, and shipped discreetly to your door.

3.Receive continuous support
Start with one goal, then keep building over time. Unlimited physician messaging, easy refills and dose adjustments, all from the Zepym Health app.

Female Desire educational content reviewed by our physician
Scott Nass, MDDoctor of Medicine, board-certified in Family Medicine
Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.
Dissolved under the tongue, as needed, 20–30 min before. The starting prescription is one troche each time. Your physician sets your own dose and it is printed on your label.
Apomorphine, Bremelanotide, Oxytocin, L-Theanine.
8 troches at the starting strength, shipped to your door from a licensed US pharmacy.
No. Vyleesi is an FDA-approved injection. This troche is compounded with several ingredients; it is prescribed off-label at your physician's judgment.
Hormones, stress, sleep, medications (especially antidepressants), relationship factors and menopause all play a part. A physician looks at the whole picture.
Sometimes. If hormones may be involved, your physician may order tests before choosing a treatment.
Yes. None of these products affect contraception.
Tell your physician. There are other options, including hormone therapy and approved medicines.
Quad-mix troche combining three PDE5 inhibitors with apomorphine dopamine agonist for maximum potency and comprehensive mechanism.
Troche
from $79/mo
Combination of papaverine and phentolamine for intracavernosal injection. Vasodilator mix for erectile dysfunction. Priapism risk and rescue requirements.
Injection
from $171/mo
Topical cream for female sexual enhancement and orgasm support. Combination of arginine, ergoloid, pentoxifylline, sildenafil, and theophylline.
Cream
from $159/mo
Topical cream for female sexual arousal and pleasure. Contains oxytocin, theophylline, arginine, and sildenafil for enhanced sensation and response.
Cream
from $189/mo
The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Individual results vary.
Bremelanotide for hypoactive sexual desire disorder: two randomized phase 3 trials.
Obstet Gynecol, 2019Hyaluronic acid vaginal gel versus estriol cream for vaginal dryness in postmenopausal women.
PubMedFemale Desire Trochesfrom $69/mo