Estradiol Cypionate
Long-acting estradiol injection for menopause and perimenopause symptoms and for gender-affirming hormone therapy, given every one to two weeks. Prescribed and dosed by a licensed physician.
Injection
from $139/mo
Injected into the muscle · Once a week
TestosteroneInjectableFDA-approved
Testosterone Cypionate (Commercial)
Commercial pharmaceutical-grade testosterone cypionate: FDA-approved, 200 mg/mL typical strength. Weekly or biweekly injection in MCT or grapeseed oil. Consistent pharmaceutical standards.
- FDA-approved pharmaceutical grade
- Consistent potency and purity
- Weekly or biweekly injection, steady levels
- Monthly$219/mo
- Every 3 months$537 billed up front$179/mo
- Every 6 monthsBest value$894 billed up front$149/mo
- Free, discreet shipping
- Licensed U.S. pharmacy
- Board-certified physicians
Disclaimer: Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Compounded medications are not FDA-approved brand-name products.
- How
- Injected into the muscle
- How often
- Once a week
- Each shipment
- 1 vial
- Strengths
- 2 options · 50–100 mg
What is commercial testosterone cypionate?
(kom-ER-shal)
Commercial testosterone cypionate is a pharmaceutical-grade formulation, FDA-approved for testosterone replacement therapy. Typical concentration: 200 mg/mL in MCT or grapeseed oil. Injected subcutaneously or intramuscularly, once or twice weekly. It meets rigorous pharmaceutical standards for purity and potency, unlike compounded formulations.
What's in it
- Testosterone CypionateReplaces low testosterone
FDA-approved
pharmaceutical-grade; meets USP standards
Commercial testosterone cypionate is regulated as a pharmaceutical product, ensuring consistent potency. It is available through licensed pharmacies. Weekly dosing provides steady testosterone levels.
Is it right for you?
Who it's for
Men who want the standard, FDA-approved testosterone injection.
What sets it apart
The commercial vial in cottonseed oil, the most prescribed testosterone in the United States.
Worth knowing before you start
Splitting the weekly dose in two smaller injections evens out the highs and lows.
What to expect
Sustained energy and libido
steady testosterone supports mood and sexual function
Improved muscle and strength
testosterone builds lean mass over 4–12 weeks
Lab-monitored
hematocrit, PSA, BP, lipids tracked regularly
Home injection
self-injection at home once or twice weekly
How injectable testosterone works
Day 1
US-licensed physician reviews testosterone goals, medical history, and baseline labs (testosterone, hematocrit, PSA, lipids, BP).
1Week 1
Teach injection technique. Start testosterone injection (weekly or biweekly). Most men learn to self-inject at home in minutes.
2Week 4
Blood work checks testosterone level. If low, dose is increased. If target is reached, dose is maintained.
3Month 2–3
Follow-up labs (testosterone, hematocrit, PSA, lipids, BP). Symptoms (energy, mood, libido, strength) reviewed.
4Beyond
Testosterone monitored every 3–6 months; hematocrit and PSA every 6–12 months; BP every 3–6 months. Dose adjusted to keep testosterone in target range.
5
Individual results vary. Benefits reflect what Zepym Health members commonly report to their physician at check-ins; they are not the results of a clinical trial.
How you use it
This is the starting dose the pharmacy prints on the label. Your physician sets yours and adjusts it with you.
- How
- Injected into the muscle
- Dose
- 0.5 mL (50 mg)
- How often
- Once a week
- Each shipment
- 1 vial
- Pharmacy label
- Inject 0.5 mL (50 mg) intramuscularly once weekly for 4 weeks. Discard any remaining medication.
A sample week
- M
- T
- W
- T
- F
- S
- S
Once a week
Strengths the pharmacy carries
- 200 mg/mL
- 100 mg/mL
The science of injectable testosterone
Commercial testosterone cypionate delivers physiologic testosterone replacement, meeting Endocrine Society guidelines for men with symptomatic hypogonadism.
Pharmaceutical-grade formulations undergo rigorous testing for potency, purity, and sterility, providing consistency that compounded formulations may not guarantee.
Learn moreImportant safety information and common side effects
Injectable testosterone (cypionate, enanthate) carries the same safety profile as all testosterone therapy: elevated hematocrit (polycythemia), blood pressure elevation, PSA increase, reduced fertility during therapy, and clotting concerns. Polycythemia (high red cell count) is monitored with hematocrit tests every 6–12 months; if hematocrit rises above 54%, testosterone is held or reduced. PSA is checked at baseline and annually. Blood pressure is monitored every 3–6 months. Tell your physician about high blood pressure, blood clotting disorders, prostate cancer concerns, or fertility plans. Common injection-site reactions are mild (redness, soreness) and resolve in days. Stop and seek care for chest pain, shortness of breath, leg swelling, severe injection-site reactions, or signs of stroke.
Every plan includes
- Personalized, physician-guided plan
- Monthly, 3-month and 6-month plans
- Dispensed by a US-licensed compounding pharmacy
- Unlimited protocol adjustments and messaging
- Ongoing support and check-ins
- Pause or cancel anytime
- Reviewed by our in-house physicians
How it works
1.Connect with a physician
Answer a few questions online and a US-licensed physician reviews your health, history and goals to make sure treatment is right for you. 100% online. No in-person visit required.
2.Get your discreet shipment
If approved, your treatment is compounded by a US-licensed, LegitScript-certified pharmacy, inspected for quality, and shipped discreetly to your door.
3.Receive continuous support
Start with one goal, then keep building over time. Unlimited physician messaging, easy refills and dose adjustments, all from the Zepym Health app.
Testosterone cypionate (commercial) educational content reviewed by our physician
Scott Nass, MDDoctor of Medicine, board-certified in Family Medicine
Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.
Frequently asked questions
How do I use Testosterone Cypionate (Commercial)?
Injected into the muscle, once a week. The starting prescription is 0.5 mL (50 mg) each time. Your physician sets your own dose and it is printed on your label.
What strengths does Testosterone Cypionate (Commercial) come in?
The pharmacy carries 2: 100 mg/mL, 200 mg/mL. Your physician chooses which one you get.
How much arrives in each shipment?
1 vial at the starting strength, shipped to your door from a licensed US pharmacy.
Is it a controlled substance?
Yes. The law requires a live video visit with the physician before it can be prescribed.
What is the difference between commercial and compounded testosterone?
Commercial testosterone is FDA-approved, pharmaceutical-grade, and meets USP (United States Pharmacopeia) standards for purity and potency. Compounded testosterone is prepared by a pharmacy to order, allowing customization but without FDA oversight. Your physician chooses based on availability, cost, and your needs.
How do I inject testosterone?
Your physician or nurse teaches you the technique in the first visit. Most men learn subcutaneous (under the skin) injection in seconds and feel comfortable within days. Intramuscular injection (into muscle) is also an option. Injections are done at home, typically once or twice per week.
What if my hematocrit rises?
Hematocrit (red blood cell count) can rise on testosterone. If it exceeds 54%, your physician may reduce your testosterone dose, have you donate blood, or pause therapy until it normalizes. Monitor hematocrit every 6–12 months.
Will testosterone affect my fertility?
Exogenous testosterone suppresses your body's natural testosterone production (testicular shutdown) and reduces sperm production. This is reversible: within 3–12 months of stopping testosterone, fertility usually returns. To preserve fertility during therapy, your physician may prescribe clomiphene or hCG alongside testosterone.
Testosterone replacement via weekly or biweekly injection.
Gonadorelin
A copy of the brain's own GnRH signal that keeps the testes producing testosterone and sperm, used alongside testosterone therapy and in fertility care. Prescribed and dosed by a licensed physician.
Injection
from $159/mo
7-Keto DHEA Capsules
7-Keto DHEA, a metabolite of DHEA that does not convert to testosterone or estrogen. Supports energy and metabolism without hormonal side effects.
Capsule
from $79/mo
Anastrozole - Men
A low-dose aromatase inhibitor for men on testosterone therapy whose blood work shows high estradiol, easing breast tenderness and water retention. Slow-release capsule, prescribed and dosed by a licensed physician.
Capsule
from $54/mo
The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Individual results vary.
Sources
- 1
Endocrine Society Clinical Practice Guidelines for testosterone therapy: dosing, monitoring, and complications.
J Clin Endocrinol Metab, 2018 - 2
TRAVERSE trial: testosterone replacement and cardiovascular outcomes in hypogonadal men.
N Engl J Med, 2021
Testosterone Cypionate (Commercial)from $149/mo