Sermorelin Injection
A growth hormone-releasing peptide that supports deeper sleep, faster recovery and lean muscle by working with your body's own rhythm.
Injection
from $179/mo
Injected under the skin · 5 days a week
Research peptide stackMoodMental clarity
Pinealon + PE-22-28 + Selank
Three bioregulatory peptides: Pinealon (pineal peptide for mood), PE-22-28 (experimental antidepressant), Selank (anxiolytic). Subcutaneous or intranasal. Very early-stage human evidence; mechanisms suggest mood and clarity support.
- Pinealon for mood and emotional resilience
- PE-22-28 as an experimental antidepressant
- Selank for calm; combined for synergistic mental support
- Monthly$329/mo
- Every 3 months$777 billed up front$259/mo
- Every 6 monthsBest value$1,374 billed up front$229/mo
- Free, discreet shipping
- Licensed U.S. pharmacy
- Board-certified physicians
Disclaimer: Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Compounded medications are not FDA-approved brand-name products.
- How
- Injected under the skin
- How often
- 5 days a week
- Each shipment
- 1 vial
- Strength
- 2 mg / 2 mg / 2 mg/mL
What is Pinealon + PE-22-28 + Selank?
(pineal bioregulator + experimental peptide + anxiolytic)
Pinealon is a peptide derived from the pineal gland, studied for mood regulation. PE-22-28 is an experimental peptide with antidepressant-like activity in preclinical models. Selank (tuftsine analog) provides anxiolytic support. The combination is given as subcutaneous injections or intranasal spray. Human evidence for this stack is very early; mechanisms are promising in animal models.
What's in it
- PinealonStudied for mood and brain function
- PE-22-28Studied for mood and brain function
- SelankStudied for calm and stress
Very early
human evidence; strong preclinical models
This combination is experimental. Pinealon, PE-22-28, and Selank each have preclinical data; combined human use is based on clinical judgment. Your physician explains the early stage and monitors mood closely.
Is it right for you?
Who it's for
Adults looking for help with mood and mental clarity who are not on psychiatric medicine.
What sets it apart
Three brain-acting peptides in one vial. The blend has never been studied in people.
Worth knowing before you start
It is not a treatment for depression or anxiety. If your mood gets worse, stop and tell your physician.
What to expect
Patience required
early-stage therapies take time; effects build over weeks
Improved sleep or mood
tracking with a journal helps you see the changes
Better focus or calm
cognitive clarity or reduced stress as peptides work
Physician partnership
close communication ensures your safety and response
How neuro peptides work
Day 1
A US-licensed physician reviews your sleep, mood, or cognitive goals, health history, and current medications. Discusses how these early-stage peptides work and the evidence gaps.
1Week 1
Start with a subcutaneous injection or intranasal spray at bedtime (or as directed). Most people find the routine comfortable within days.
2Weeks 2–4
Sleep quality, mood, or focus may begin to shift. Some notice changes within days; others take 3–4 weeks. Keep a sleep or mood journal.
3Month 2
Your physician checks in, reviews your journal, and adjusts dose if needed. Discuss any changes in sleep, mood, energy, or focus.
4Beyond
Neuro peptides work best with consistent use. Your physician monitors your response every 4–6 weeks and adjusts as your needs change.
5
Individual results vary. Benefits reflect what Zepym Health members commonly report to their physician at check-ins; they are not the results of a clinical trial.
How you use it
This is the starting dose the pharmacy prints on the label. Your physician sets yours and adjusts it with you.
- How
- Injected under the skin
- Dose
- 20 units (0.4 mg)
- How often
- 5 days a week
- Each shipment
- 1 vial
- Pharmacy label
- Inject 20 units (0.4 mg) subcutaneously once daily 5 days per week for 4 weeks. Discard any remaining medication.
A sample week
- M
- T
- W
- T
- F
- S
- S
5 days a week
The science of neuro peptides
Pinealon supports circadian rhythm and mood-related neurotransmitter systems. PE-22-28 shows antidepressant effects in animal models. Selank dampens anxiety via immune peptide pathways.
Direct human trials of this combination do not exist. Your physician uses it based on the mechanistic reasoning and early clinical experience. A mood journal and regular check-ins are essential to gauge response.
Learn moreImportant safety information and common side effects
Neuro peptides are prescribed off-label based on preclinical and early clinical evidence. Common mild effects include injection-site reactions, headache, or temporary sleep changes in the first week. DSIP, Semax, and Selank are not prescribed during pregnancy or breastfeeding, or with active psychiatric medication without careful discussion—some combinations require monitoring or dose adjustment. Tell your physician about every medication, supplement, and any history of seizures or psychosis. Stop and seek care for severe headache, agitation, mood changes that interfere with daily life, or signs of allergic reaction.
Every plan includes
- Personalized, physician-guided plan
- Monthly, 3-month and 6-month plans
- Dispensed by a US-licensed compounding pharmacy
- Unlimited protocol adjustments and messaging
- Ongoing support and check-ins
- Pause or cancel anytime
- Reviewed by our in-house physicians
How it works
1.Connect with a physician
Answer a few questions online and a US-licensed physician reviews your health, history and goals to make sure treatment is right for you. 100% online. No in-person visit required.
2.Get your discreet shipment
If approved, your treatment is compounded by a US-licensed, LegitScript-certified pharmacy, inspected for quality, and shipped discreetly to your door.
3.Receive continuous support
Start with one goal, then keep building over time. Unlimited physician messaging, easy refills and dose adjustments, all from the Zepym Health app.
Pinealon + PE-22-28 + Selank educational content reviewed by our physician
Scott Nass, MDDoctor of Medicine, board-certified in Family Medicine
Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.
Frequently asked questions
How do I use Pinealon / PE-22-28 / Selank?
Injected under the skin, 5 days a week. The starting prescription is 20 units (0.4 mg) each time. Your physician sets your own dose and it is printed on your label.
What exactly is in it?
Pinealon, PE-22-28, Selank.
How much arrives in each shipment?
1 vial at the starting strength, shipped to your door from a licensed US pharmacy.
Why is this combination so experimental?
Pinealon, PE-22-28, and Selank each have preclinical support, but combined human trials do not exist. Your physician assembles them based on complementary mechanisms: mood support (Pinealon + PE-22-28) + anxiety relief (Selank). This is research-stage medicine; close communication with your physician is critical.
Why are these off-label?
Off-label means not FDA-approved for these uses, but prescribed by physicians based on preclinical research and clinical experience. It is common in medical practice, especially for emerging therapies. Your physician explains what is known and what remains uncertain.
Can I combine these with other medications?
Tell your physician about every medication, especially psychiatric drugs (SSRIs, antipsychotics), stimulants, or sleep aids. Some combinations need careful timing, dose adjustment, or extra monitoring. Do not start or stop any other medications without discussing with your physician.
What if I don't notice a change?
Some people respond quickly; others take 4–8 weeks. Keep a detailed sleep or mood journal to spot subtle changes. If no response after 6–8 weeks, your physician may adjust the dose, try a different peptide, or explore other options.
Are these safe long-term?
Long-term safety data are limited because human use is recent. Your physician monitors you regularly and reassesses the plan every 3–6 months. If any concerning symptoms arise, stop immediately and report them.
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The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Individual results vary.
Sources
- 1
Delta sleep-inducing peptide (DSIP): a review of its effects on sleep.
Sleep Med Rev, 2003 - 2
Semax: a novel neuropeptide candidate for cognitive enhancement and neuroprotection.
Ann NY Acad Sci, 2005
Pinealon + PE-22-28 + Selankfrom $229/mo