Sermorelin Injection
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Injection
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Injected under the skin · 5 days a week
Research peptideTanningLibido
Melanotan II
Melanotan II: a melanocyte-stimulating hormone (MSH) analog that promotes tanning and increases sexual interest. NOT FDA-approved; requires skin check before starting and ongoing mole monitoring. Subcutaneous injection. Requires frank safety discussion with your physician.
- Activates melanin production for gradual tanning without sun
- Increases sexual interest and arousal in many users
- Users report sustained results with maintenance dosing
- Monthly$299/mo
- Every 3 months$717 billed up front$239/mo
- Every 6 monthsBest value$1,254 billed up front$209/mo
- Free, discreet shipping
- Licensed U.S. pharmacy
- Board-certified physicians
Disclaimer: Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Compounded medications are not FDA-approved brand-name products.
- How
- Injected under the skin
- How often
- 5 days a week
- Each shipment
- 1 vial
- Strength
- 2 mg/mL
What is Melanotan II?
(melanocyte-stimulating hormone analog)
Melanotan II is a synthetic analog of alpha-melanocyte-stimulating hormone (MSH), which signals melanocytes (pigment cells) to produce more melanin. It also activates receptors in the brain and body linked to sexual interest and arousal. It is NOT approved by the FDA for any use. Melanotan II is compounded off-label, dosed as subcutaneous injections. Important: skin cancer risk requires careful discussion and ongoing monitoring.
What's in it
- Melanotan IISignals skin to make pigment
NOT FDA-approved
research peptide with real risks and benefits
Melanotan II carries safety concerns: melanoma risk (though literature is mixed), erections lasting hours in some men, and darkening of existing moles. A baseline skin exam with dermoscopy and regular checks are mandatory.
Is it right for you?
Who it's for
Adults who want a tan and accept that health agencies advise against it.
What sets it apart
It makes the skin produce pigment without sun. It also darkens moles and causes nausea and spontaneous erections.
Worth knowing before you start
See a dermatologist for a full skin check before starting. A tan from it does not protect you from the sun.
Results you can see and feel
Sun-free tan (Melanotan II)
gradual deepening of skin tone without UV
Sexual interest (PT-141)
on-demand boost in desire and arousal
Confidence
both improve appearance or intimacy confidence
Safety monitoring required
dermatology for Melanotan II, BP for PT-141
How melanocortin peptides work
Day 1
A US-licensed physician reviews your goals, medical history, and medications. For Melanotan II, a dermatologist clears your skin. For PT-141, your BP and cardiac history are checked.
1Week 1
For Melanotan II: small doses start the tanning process. For PT-141: first dose is tested privately to confirm tolerance and response.
2Week 2–4
Melanotan II: tan develops gradually over weeks. PT-141: sexual interest and arousal increase predictably on-demand.
3Month 2
Your physician checks in: Melanotan II users report on tanning progress and any mole changes (dermatology follow-up required). PT-141 users discuss sexual satisfaction and any side effects.
4Beyond
Melanotan II: ongoing dermatology checks are non-negotiable. PT-141: use as-needed; your physician reviews annually or if changes occur.
5
Individual results vary. Benefits reflect what Zepym Health members commonly report to their physician at check-ins; they are not the results of a clinical trial.
How you use it
This is the starting dose the pharmacy prints on the label. Your physician sets yours and adjusts it with you.
- How
- Injected under the skin
- Dose
- 20 units (0.4 mg)
- How often
- 5 days a week
- Each shipment
- 1 vial
- Pharmacy label
- Inject 20 units (0.4 mg) subcutaneously once daily 5 days per week for 4 weeks. Discard any remaining medication.
A sample week
- M
- T
- W
- T
- F
- S
- S
5 days a week
The science of melanocortin peptides
Melanotan II increases melanin synthesis, producing a gradual tan without UV exposure. It also activates melanocortin receptors in the hypothalamus and peripheral tissues, increasing sexual interest.
Safety data are limited. Melanoma risk is debated in the literature—some studies suggest increased risk, others do not. Your dermatologist must evaluate your skin, establish baseline mole counts, and follow you closely.
Learn moreImportant safety information and common side effects
Melanotan II and PT-141 activate melanocortin receptors throughout the body, with different safety profiles. Melanotan II: melanoma risk is the primary concern; baseline skin exam with dermoscopy and regular mole checks are mandatory. Darkening of existing moles can make monitoring harder. PT-141: nausea is common (30–50%), usually mild; do not use with uncontrolled high blood pressure, recent MI, unstable angina, or severe heart disease. In men, priapism (erection lasting >4 hours) is rare but requires immediate care. Tell your physician about blood pressure medications, heart history, and any skin concerns. Stop and seek care for severe headache, chest pain, priapism, severe nausea, or signs of allergic reaction.
Every plan includes
- Personalized, physician-guided plan
- Monthly, 3-month and 6-month plans
- Dispensed by a US-licensed compounding pharmacy
- Unlimited protocol adjustments and messaging
- Ongoing support and check-ins
- Pause or cancel anytime
- Reviewed by our in-house physicians
How it works
1.Connect with a physician
Answer a few questions online and a US-licensed physician reviews your health, history and goals to make sure treatment is right for you. 100% online. No in-person visit required.
2.Get your discreet shipment
If approved, your treatment is compounded by a US-licensed, LegitScript-certified pharmacy, inspected for quality, and shipped discreetly to your door.
3.Receive continuous support
Start with one goal, then keep building over time. Unlimited physician messaging, easy refills and dose adjustments, all from the Zepym Health app.
Melanotan II educational content reviewed by our physician
Scott Nass, MDDoctor of Medicine, board-certified in Family Medicine
Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.
Frequently asked questions
How do I use Melanotan II?
Injected under the skin, 5 days a week. The starting prescription is 20 units (0.4 mg) each time. Your physician sets your own dose and it is printed on your label.
How much arrives in each shipment?
1 vial at the starting strength, shipped to your door from a licensed US pharmacy.
Is Melanotan II safe?
Short answer: not established. It is not FDA-approved. The main concerns are melanoma risk (literature is mixed but precaution is warranted), darkening of existing moles (which can make monitoring harder), and in men, priapism (prolonged erection). A dermatologist must clear you, establish baselines, and follow you. It is only chosen by those who understand and accept these risks.
How long until I see results?
Melanotan II: tan develops over 1–4 weeks of consistent dosing; deepens over months. PT-141: sexual effects appear within 1–2 hours of injection, peak around 2 hours, last several hours. Both require consistent use or dosing to maintain results.
What if I have side effects?
Melanotan II: darkening of moles, nausea, or erections in some men. Report all mole changes to your dermatologist immediately. PT-141: nausea is common (30–50%); anti-nausea medication beforehand helps. Rare: priapism in men (erection >4 hours)—seek emergency care. Stop immediately if any severe reaction occurs.
Can I use these with other medications?
Tell your physician about all medications, especially blood pressure drugs or cardiac medications. Some combinations need monitoring. Do not use Melanotan II with a personal or family history of melanoma without careful discussion with dermatology.
How long do I use these?
Melanotan II: as long as you want the tan; dermatology checks remain mandatory. PT-141: as-needed indefinitely, or until your sexual health goals change. Annual check-ins with your physician are recommended.
Appearance and intimacy, informed choice.
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The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Individual results vary.
Sources
- 1
Melanotan II and its analogues as potential therapeutics for sexual dysfunction and other disorders.
Nat Rev Drug Discov, 2009 - 2
Bremelanotide for hypoactive sexual desire disorder in women: a randomized, placebo-controlled trial.
Obstet Gynecol, 2018
Melanotan IIfrom $209/mo