Zepym Health
LL-37

Injected under the skin · 5 days a week

Research peptideImmune

LL-37

A research peptide derived from human antimicrobial proteins, studied for immune modulation and inflammation, used to support immune and skin health.

  • Derived from your own immune system's antimicrobial peptide
  • Early research in humans; most evidence is laboratory
  • Subcutaneous injection, dosed by your physician
  • Monthly$299/mo
  • Every 3 months$717 billed up front$239/mo
  • Every 6 monthsBest value$1,254 billed up front$209/mo
  • Free, discreet shipping
  • Licensed U.S. pharmacy
  • Board-certified physicians

Disclaimer: Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Compounded medications are not FDA-approved brand-name products.

How
Injected under the skin
How often
5 days a week
Each shipment
1 vial
Strength
2 mg/mL

What is LL-37?

(cathelicidin-related antimicrobial peptide)

LL-37 is a fragment of human cathelicidin, an antimicrobial peptide your immune system makes. Beyond killing bacteria directly, it modulates immune signaling and may reduce excessive inflammation. It is prescribed off-label based on preclinical evidence and growing clinical interest, not approved trials.

What's in it

  • LL-37Antimicrobial peptide

Early

human evidence for LL-37 in immune and skin applications

Most research is in cell cultures and animal models. Injectable LL-37 is prescribed off-label at your physician's discretion.

Is it right for you?

  • Who it's for

    Adults who want an immune peptide and have no psoriasis or rosacea.

  • What sets it apart

    An antimicrobial peptide the body makes itself. Injecting it has not been studied in trials.

  • Worth knowing before you start

    High LL-37 in the skin is part of psoriasis and rosacea. If either flares, stop.

What to expect

  • Slower feedback

    early-stage therapies take time and close monitoring

  • Individual response

    outcomes vary widely because evidence is limited

  • Physician partnership

    your role is to communicate closely at every check-in

  • Informed choice

    you understand the evidence gap before starting

How research peptides work

  1. Day 1

    A US-licensed physician reviews your goal, health history and reasons to try this early-stage peptide. You discuss the evidence and the unknowns together.

    1
  2. Week 1

    A small subcutaneous injection, usually in the abdomen or near the site you're treating. Most people find the routine comfortable within days.

    2
  3. Week 2–4

    Signaling and recovery processes begin. Many report improved energy or easier movement, depending on the peptide.

    3
  4. Month 2+

    Your physician checks in, adjusts dose if needed, and follows relevant labs (IGF-1, immune markers, etc.). Tell them everything you notice.

    4

Individual results vary. Benefits reflect what Zepym Health members commonly report to their physician at check-ins; they are not the results of a clinical trial.

How you use it

This is the starting dose the pharmacy prints on the label. Your physician sets yours and adjusts it with you.

How
Injected under the skin
Dose
20 units (0.4 mg)
How often
5 days a week
Each shipment
1 vial
Pharmacy label
Inject 20 units (0.4 mg) subcutaneously once daily 5 days per week for 4 weeks. Discard any remaining medication.

A sample week

  1. M
  2. T
  3. W
  4. T
  5. F
  6. S
  7. S

5 days a week

The science of research peptides

In laboratory studies, LL-37 activates immune cells, reduces inflammatory cytokines, and has antimicrobial effects. It is being explored for skin and wound healing.

Human clinical data are very limited. Your physician explains the early stage of this evidence and follows how you respond at check-ins.

Learn more

Important safety information and common side effects

Research peptides are prescribed off-label and carry more uncertainty than established therapies. Common, mild effects include redness, itching or a bump at the injection site, headache, or flushing in the first days. Because these peptides support cell growth or immune signaling, they are not prescribed with an active cancer, a cancer under evaluation, or during pregnancy or breastfeeding. Some (IGF-1) require careful glucose monitoring. Tell your physician about every medication you take, every supplement, and your complete health history, including any autoimmune conditions. Stop and seek care for hives, swelling of the face or lips, or trouble breathing.

Every plan includes

  • Personalized, physician-guided plan
  • Monthly, 3-month and 6-month plans
  • Dispensed by a US-licensed compounding pharmacy
  • Unlimited protocol adjustments and messaging
  • Ongoing support and check-ins
  • Pause or cancel anytime
  • Reviewed by our in-house physicians
Get Started

How it works

  1. 1.Connect with a physician

    Answer a few questions online and a US-licensed physician reviews your health, history and goals to make sure treatment is right for you. 100% online. No in-person visit required.

  2. 2.Get your discreet shipment

    If approved, your treatment is compounded by a US-licensed, LegitScript-certified pharmacy, inspected for quality, and shipped discreetly to your door.

  3. 3.Receive continuous support

    Start with one goal, then keep building over time. Unlimited physician messaging, easy refills and dose adjustments, all from the Zepym Health app.

LL-37 educational content reviewed by our physician

Scott Nass, MDDoctor of Medicine, board-certified in Family Medicine

Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.

Frequently asked questions

How do I use LL-37?

Injected under the skin, 5 days a week. The starting prescription is 20 units (0.4 mg) each time. Your physician sets your own dose and it is printed on your label.

How much arrives in each shipment?

1 vial at the starting strength, shipped to your door from a licensed US pharmacy.

Who uses LL-37?

People interested in immune support or with persistent skin or inflammatory conditions who want to explore an emerging option. Your physician reviews your history and decides whether to trial it; it is not prescribed with active infection without careful discussion.

Why are these off-label?

Off-label means not FDA-approved for these specific uses, but prescribed by physicians based on preclinical evidence and clinical experience. It is common in medical practice; your physician explains the evidence and the gaps.

How often do I take it?

Usually a small subcutaneous injection once daily or a few times a week, depending on the peptide. Your physician sets the schedule and adjusts it as needed. The kit includes everything.

What is the evidence really like?

Honest answer: early. Preclinical and animal data are promising; human data are limited or absent. Your physician explains this plainly and monitors you closely. If you prefer established therapies, tell them.

Research peptides require partnership.

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Answer a few questions and take your first step to living well.

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The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Individual results vary.

Sources

  1. 1

    Mechanisms of IGF-1-Mediated Regulation of Skeletal Muscle Hypertrophy and Atrophy.

    Cells, 2020
  2. 2

    Unique features of human cathelicidin LL-37.

    Biofactors, 2015
  3. 3

    Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing.

    Curr Rev Musculoskelet Med, 2025
  4. 4

    Metabolic effects of a growth hormone-releasing factor (tesamorelin) in patients with HIV.

    N Engl J Med, 2007
  5. 5

    Ipamorelin, the first selective growth hormone secretagogue.

    Eur J Endocrinol, 1998
  6. 6

    Thymosin alpha 1: A comprehensive review of the literature.

    World J Virol, 2020

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