Sermorelin Injection
A growth hormone-releasing peptide that supports deeper sleep, faster recovery and lean muscle by working with your body's own rhythm.
Injection
from $179/mo
Injected under the skin · 5 days a week
Research peptideTissue repair
IGF-1 LR3
A research peptide studied for cell growth and tissue repair, used off-label to support muscle recovery and strength after injury.
- Studied for tissue growth and repair signaling
- Early research in humans; most evidence is preclinical
- Subcutaneous injection, dosed by your physician
- Monthly$249/mo
- Every 3 months$597 billed up front$199/mo
- Every 6 monthsBest value$1,044 billed up front$174/mo
- Free, discreet shipping
- Licensed U.S. pharmacy
- Board-certified physicians
Disclaimer: Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Compounded medications are not FDA-approved brand-name products.
- How
- Injected under the skin
- How often
- 5 days a week
- Each shipment
- 1 vial
- Strength
- 200 mcg/mL
What is IGF-1 LR3?
(insulin-like growth factor 1, long-acting analog)
IGF-1 LR3 is a modified version of insulin-like growth factor 1, a hormone your body makes to drive cell growth and tissue repair. The 'LR3' modification makes it longer-acting than natural IGF-1. It is prescribed off-label based on preclinical evidence and clinical experience, not approved trials.
What's in it
- IGF-1 LR3Growth factor: muscle recovery
Preclinical
most evidence for IGF-1 in tissue repair and muscle growth
Human clinical trials of IGF-1 are limited. IGF-1 LR3 is prescribed off-label at your physician's discretion; they monitor IGF-1 levels and blood glucose closely.
Is it right for you?
Who it's for
Experienced adults focused on muscle recovery who understand the risks.
What sets it apart
It is not a signal to release growth hormone: it is a long-acting form of IGF-1 itself, the hormone growth hormone works through.
Worth knowing before you start
It lowers blood sugar like insulin. Always inject it after a meal, never before training on an empty stomach.
What to expect
Slower feedback
early-stage therapies take time and close monitoring
Individual response
outcomes vary widely because evidence is limited
Physician partnership
your role is to communicate closely at every check-in
Informed choice
you understand the evidence gap before starting
How research peptides work
Day 1
A US-licensed physician reviews your goal, health history and reasons to try this early-stage peptide. You discuss the evidence and the unknowns together.
1Week 1
A small subcutaneous injection, usually in the abdomen or near the site you're treating. Most people find the routine comfortable within days.
2Week 2–4
Signaling and recovery processes begin. Many report improved energy or easier movement, depending on the peptide.
3Month 2+
Your physician checks in, adjusts dose if needed, and follows relevant labs (IGF-1, immune markers, etc.). Tell them everything you notice.
4
Individual results vary. Benefits reflect what Zepym Health members commonly report to their physician at check-ins; they are not the results of a clinical trial.
How you use it
This is the starting dose the pharmacy prints on the label. Your physician sets yours and adjusts it with you.
- How
- Injected under the skin
- Dose
- 20 units (40 mcg)
- How often
- 5 days a week
- When
- At bedtime
- Each shipment
- 1 vial
- Pharmacy label
- Inject 20 units (40 mcg) subcutaneously after your evening meal once daily 5 days per week for 4 weeks. Discard any remaining medication.
A sample week
- M
- T
- W
- T
- F
- S
- S
5 days a week
The science of research peptides
In animal models, IGF-1 stimulates muscle protein synthesis, improves recovery after injury, and supports tissue repair through multiple pathways.
Human evidence is very early. Your physician explains this gap and monitors you closely, including blood glucose and IGF-1 levels, because high IGF-1 raises cancer risk questions your physician addresses.
Learn moreImportant safety information and common side effects
Research peptides are prescribed off-label and carry more uncertainty than established therapies. Common, mild effects include redness, itching or a bump at the injection site, headache, or flushing in the first days. Because these peptides support cell growth or immune signaling, they are not prescribed with an active cancer, a cancer under evaluation, or during pregnancy or breastfeeding. Some (IGF-1) require careful glucose monitoring. Tell your physician about every medication you take, every supplement, and your complete health history, including any autoimmune conditions. Stop and seek care for hives, swelling of the face or lips, or trouble breathing.
Every plan includes
- Personalized, physician-guided plan
- Monthly, 3-month and 6-month plans
- Dispensed by a US-licensed compounding pharmacy
- Unlimited protocol adjustments and messaging
- Ongoing support and check-ins
- Pause or cancel anytime
- Reviewed by our in-house physicians
How it works
1.Connect with a physician
Answer a few questions online and a US-licensed physician reviews your health, history and goals to make sure treatment is right for you. 100% online. No in-person visit required.
2.Get your discreet shipment
If approved, your treatment is compounded by a US-licensed, LegitScript-certified pharmacy, inspected for quality, and shipped discreetly to your door.
3.Receive continuous support
Start with one goal, then keep building over time. Unlimited physician messaging, easy refills and dose adjustments, all from the Zepym Health app.
IGF-1 LR3 educational content reviewed by our physician
Scott Nass, MDDoctor of Medicine, board-certified in Family Medicine
Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.
Frequently asked questions
How do I use IGF-1 LR3?
Injected under the skin, 5 days a week, at bedtime. The starting prescription is 20 units (40 mcg) each time. Your physician sets your own dose and it is printed on your label.
How much arrives in each shipment?
1 vial at the starting strength, shipped to your door from a licensed US pharmacy.
How is IGF-1 LR3 prescribed?
Off-label, based on clinical experience rather than large trials. Your physician reviews your health history carefully, sets a conservative dose, and checks IGF-1 and glucose regularly. It is not prescribed with a cancer history or diabetes without careful discussion.
Why are these off-label?
Off-label means not FDA-approved for these specific uses, but prescribed by physicians based on preclinical evidence and clinical experience. It is common in medical practice; your physician explains the evidence and the gaps.
How often do I take it?
Usually a small subcutaneous injection once daily or a few times a week, depending on the peptide. Your physician sets the schedule and adjusts it as needed. The kit includes everything.
What is the evidence really like?
Honest answer: early. Preclinical and animal data are promising; human data are limited or absent. Your physician explains this plainly and monitors you closely. If you prefer established therapies, tell them.
Research peptides require partnership.
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The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Individual results vary.
Sources
- 1
Mechanisms of IGF-1-Mediated Regulation of Skeletal Muscle Hypertrophy and Atrophy.
Cells, 2020 - 2
Unique features of human cathelicidin LL-37.
Biofactors, 2015 - 3
Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing.
Curr Rev Musculoskelet Med, 2025 - 4
Metabolic effects of a growth hormone-releasing factor (tesamorelin) in patients with HIV.
N Engl J Med, 2007 - 5
Ipamorelin, the first selective growth hormone secretagogue.
Eur J Endocrinol, 1998 - 6
Thymosin alpha 1: A comprehensive review of the literature.
World J Virol, 2020
IGF-1 LR3from $174/mo