Estradiol Cypionate
Long-acting estradiol injection for menopause and perimenopause symptoms and for gender-affirming hormone therapy, given every one to two weeks. Prescribed and dosed by a licensed physician.
Injection
from $139/mo
Injected into the muscle · Once a week
MuscleAnemiaJoint painControlled substance
A physician-directed anabolic steroid for muscle wasting, refractory anemia, and bone loss. Given as an intramuscular injection once weekly. Requires full understanding of benefits and serious risks.
Disclaimer: Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Compounded medications are not FDA-approved brand-name products.
(NAN-dro-lone DEK-uh-noe-ate)
Nandrolone decanoate is a synthetic anabolic steroid—a controlled substance (Schedule III) that resembles testosterone but is chemically distinct and designed to emphasize muscle-building over male-pattern side effects. It is prescribed in specific contexts: muscle wasting from chronic disease, anemia that does not respond to other treatments, and bone loss or joint pain in select patients. The decanoate ester makes it long-acting—one injection lasts two to three weeks. Nandrolone is not the same as testosterone; it does not fully replace testosterone's sexual function, but it carries distinct risks of its own, including effects on cholesterol, blood cell production, and fertility. It is a controlled substance and requires a physician's close oversight.
Schedule III
the legal status of nandrolone decanoate in the United States—a controlled substance requiring prescription and careful monitoring
Nandrolone is prescribed off-label for muscle wasting and anemia at your physician's discretion. It is not an over-the-counter supplement.
Men under a physician's care for joint pain or muscle wasting.
A weekly injection with a long history in medicine for anemia and wasting. It shuts down your own testosterone.
It is usually taken with testosterone, not instead of it. Fertility is affected for months.
the primary effect in wasting conditions, usually visible within 6–8 weeks
often measurable in labs before clinically obvious
in selected conditions of bone loss
Day 1
A US-licensed physician reviews your condition—muscle wasting, anemia, or bone loss—your history, labs, and blood pressure, and determines if nandrolone is appropriate. You discuss the risks and benefits in depth.
1Week 1
Intramuscular injection of 100 mg (0.5 mL) once weekly. The injections are given at home after training, and your physician monitors your labs closely.
2Month 1–2
Increased appetite and energy often appear first. Muscle mass begins to build. Your physician checks labs (lipids, hematocrit, liver function) and blood pressure.
3Month 3
Visible muscle gain and improved strength for most patients. Your physician reviews how you feel, any mood or skin changes, labs again, and adjusts the plan.
4Beyond
Nandrolone is reassessed every 3 months. Your physician monitors ongoing labs and decides whether to continue, adjust dose, or stop based on benefit and risk.
5Individual results vary. Benefits reflect what Zepym Health members commonly report to their physician at check-ins; they are not the results of a clinical trial.
This is the starting dose the pharmacy prints on the label. Your physician sets yours and adjusts it with you.
A sample week
Once a week
Anabolic steroids have been used since the mid-20th century to treat wasting, anemia, and bone loss when other therapies fail. The evidence for nandrolone in these specific conditions is strongest; off-label use in other contexts is less well established.
Nandrolone's risks are real and dose-dependent: lipid changes, shifts in hematocrit (red blood cell concentration), virilization in women, and suppression of the body's own testosterone and sperm production. These effects do reverse after stopping, but recovery takes time. Your physician monitors labs closely.
Learn moreNandrolone is a controlled substance with serious risks. You must be fully informed before starting. Common effects include acne, hair loss or increased hair growth (body and facial in women), mood changes, sleep disruption, and injection-site reactions. Serious effects include lipid profile worsening (low HDL, high LDL), elevated hematocrit (which raises clot risk), virilization in women (voice deepening, clitoral enlargement, male-pattern baldness, beard growth), suppression of LH and FSH (which halts sperm production and shrinks testes in men), and, in women, menstrual irregularities. Nandrolone is not prescribed with a history of prostate cancer, breast cancer, high cholesterol despite treatment, polycythemia (high red blood cell count), liver disease, heart disease, or pregnancy. Long-term use increases risk of cardiovascular events. Mood changes can include aggression, which your physician monitors. Stop and seek care immediately for chest pain, shortness of breath, leg swelling, severe headache, or sudden vision changes. Women on nandrolone must use reliable contraception: it is highly teratogenic. Tell your physician about every medication you take.

1.Connect with a physician
Answer a few questions online and a US-licensed physician reviews your health, history and goals to make sure treatment is right for you. 100% online. No in-person visit required.

2.Get your discreet shipment
If approved, your treatment is compounded by a US-licensed, LegitScript-certified pharmacy, inspected for quality, and shipped discreetly to your door.

3.Receive continuous support
Start with one goal, then keep building over time. Unlimited physician messaging, easy refills and dose adjustments, all from the Zepym Health app.

Nandrolone educational content reviewed by our physician
Scott Nass, MDDoctor of Medicine, board-certified in Family Medicine
Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.
Injected into the muscle, once a week. The starting prescription is 0.5 mL (100 mg) each time. Your physician sets your own dose and it is printed on your label.
1 vial at the starting strength, shipped to your door from a licensed US pharmacy.
Yes. The law requires a live video visit with the physician before it can be prescribed.
Because it is an anabolic steroid: it builds muscle and can be misused for performance enhancement. The legal restriction requires that only licensed physicians prescribe it, patients undergo medical oversight, and records are kept. This protects public health while allowing its use in genuine medical need.
No. Both are androgens (male hormones), but nandrolone is chemically distinct and was designed to build muscle with fewer sexual effects. However, it has its own risks: lipid changes, blood-cell effects, and fertility suppression. Your physician chooses between them based on your condition.
Possibly. Nandrolone suppresses your own testosterone production, which can lower sex drive. Testicular size may shrink. These effects usually reverse after stopping, but recovery takes weeks to months. Your physician monitors and discusses this with you.
Nandrolone carries virilization risk in women: voice deepening, facial hair growth, clitoral enlargement, and male-pattern baldness may appear and can be irreversible. You must use reliable contraception—it is highly teratogenic. Your physician discusses these risks in detail.
Long-acting estradiol injection for menopause and perimenopause symptoms and for gender-affirming hormone therapy, given every one to two weeks. Prescribed and dosed by a licensed physician.
Injection
from $139/mo
A copy of the brain's own GnRH signal that keeps the testes producing testosterone and sperm, used alongside testosterone therapy and in fertility care. Prescribed and dosed by a licensed physician.
Injection
from $159/mo
7-Keto DHEA, a metabolite of DHEA that does not convert to testosterone or estrogen. Supports energy and metabolism without hormonal side effects.
Capsule
from $79/mo
A low-dose aromatase inhibitor for men on testosterone therapy whose blood work shows high estradiol, easing breast tenderness and water retention. Slow-release capsule, prescribed and dosed by a licensed physician.
Capsule
from $54/mo
The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Individual results vary.
Androgens for the anaemia of chronic kidney disease in adults.
Cochrane Database Syst Rev, 2014Effects of nandrolone decanoate compared with placebo or testosterone on HIV-associated wasting.
HIV Med, 2006Adverse Effects of Anabolic-Androgenic Steroids: A Literature Review.
Healthcare (Basel), 2021Nandrolone Decanoatefrom $179/mo