Foam
Finasteride / Minoxidil 0.25 mg / 5 mg Foam
A once-daily topical foam that combines finasteride and 5% minoxidil to slow hair loss and support regrowth; the usual starting point. Prescribed by a licensed physician.
Starting at $89/mo
Hair lossTriple action
Finasteride / Minoxidil / Tretinoin Foam, 30 mL
RxPrescription onlyApplied to the scalp · Once a day · Hair loss · Triple action
Starting at $99/mo
Finasteride, minoxidil and tretinoin in one topical foam: tretinoin helps the scalp absorb and activate minoxidil, so the other two work harder.
Choose your plan
Real prices from our pharmacy. Longer plans cost less per month and are billed up front. Pause or cancel anytime.
- Tretinoin boosts the enzyme that activates minoxidil in the scalp
- Finasteride blocks DHT at the follicle with low systemic exposure
- One foam, one application a day; 30 mL monthly supply
Every plan includes
- Personalized, physician-guided plan
- Monthly, 3-month and 6-month plans
- Dispensed by a US-licensed compounding pharmacy
- Unlimited protocol adjustments and messaging
- Ongoing support and check-ins
- Pause or cancel anytime
- Reviewed by our in-house physicians
- Physician-guided care
- Ongoing, expert support
- 100% online
- Free, discreet shipping
What is the finasteride / minoxidil / tretinoin foam?
(the three-ingredient foam)
Minoxidil only works once the scalp converts it to minoxidil sulfate, and some people have low levels of the enzyme that does that. Tretinoin, a vitamin A derivative, raises that enzyme's activity and improves penetration through the skin, which is why it is added to minoxidil for people who respond weakly. Finasteride completes the foam by blocking DHT, the hormone behind pattern hair loss. This 30 mL bottle is a one-month supply on the monthly plan.
- How it is taken
- Applied to the scalp
- How often
- Once a day
- Form
- Hair loss · Triple action
3-in-1
DHT blockade, growth-phase extension and an absorption booster in one foam
Tretinoin plus minoxidil has been reviewed as co-therapy for pattern hair loss; the triple compounded foam is prescribed off-label at your physician's discretion.
How it works,
week by week.
Day 1
A US-licensed physician reviews your pattern of loss, history and photos and chooses the foam and strength. It ships discreetly to your door.
Weeks 1–4
Apply the foam to a dry scalp once a day, on the areas that are thinning. It takes a minute and dries quickly. Some early shedding is normal: old hairs are being replaced.
Months 2–3
Shedding slows and the scalp settles. New hairs start as fine, short growth that is easy to miss without photos, which is why we ask for them.
Months 4–6
Visible change for most responders: thicker coverage at the crown and hairline. Your physician reviews photos and decides whether to adjust the strength.
Beyond
Hair-loss treatment is maintenance: results last as long as you keep applying it. Stop, and the gains reverse over months.
What you may notice,
and when.
Less shedding
usually the first change, after the initial shed
Thicker coverage
crown and hairline density over months
Loss slowed
finasteride's main job: protecting the hair you have
Confidence
the reason most members start
Individual results vary. Benefits reflect what Zepym Health members commonly report to their physician at check-ins; they are not the results of a clinical trial.
Safety first:
what to know before you start.
Important safety information and common side effects
Topical hair-loss foams are generally well tolerated. The most common effects are on the scalp: dryness, itching, redness or flaking, and a temporary increase in shedding in the first 4 to 8 weeks as old hairs make way for new growth. Minoxidil can rarely cause unwanted hair on the face or hands, dizziness or a fast heartbeat; tretinoin increases sun sensitivity and irritation. Topical finasteride reaches the bloodstream at much lower levels than the tablet, but sexual side effects (lower libido, erectile changes) and mood changes have been reported and should be told to your physician. Finasteride must not be used, handled or touched by anyone who is pregnant or may become pregnant: it can harm a male fetus. Not for use on broken or inflamed skin. Wash your hands after applying and keep the foam away from children and pets. Tell your physician about every medication you take.
The research behind
the topical hair combinations.
Each product combines drugs applied to the scalp: finasteride, dutasteride, minoxidil, latanoprost or tretinoin. Trials exist for most of these drugs on their own, mostly small. We did not find a trial of any of these exact combinations.
- Topical finasteride20.2 vs 6.7 hairs
Phase III trial of a topical finasteride spray in 458 men over 24 weeks. Hair count in the 1 cm² target area rose 20.2 hairs with the spray and 6.7 with placebo (P<0.001), numerically similar to oral finasteride at 21.1 hairs. This is a spray, not the foam or solution sold here.
Piraccini et al., J Eur Acad Dermatol Venereol 2022;36(2):286-94 - Minoxidil 5%superior to 2% at 48 weeks
Randomized trial in men with androgenetic alopecia. At 48 weeks the 5% minoxidil solution was significantly superior to 2% solution and to placebo for change in nonvellus hair count, and the response came earlier. It caused more pruritus and local irritation.
Olsen et al., J Am Acad Dermatol 2002 - Latanoprost16 men
Pilot trial of latanoprost 0.1% on one scalp site against placebo on another site in the same men, for 24 weeks. Hair density rose versus baseline and versus the placebo site (P<0.001 and P=0.0004). Sixteen men with mild loss is too few to size the effect.
Blume-Peytavi et al., J Am Acad Dermatol 2012;66(5):794-800
What the studies found
- Topical finasteride spray gave 20.2 hairs in a 1 cm² target area vs 6.7 for placebo at 24 weeks, similar to oral finasteride (Piraccini et al., J Eur Acad Dermatol Venereol 2022).
- 5% minoxidil solution gave more regrowth than 2% solution at 48 weeks in men (Olsen et al., J Am Acad Dermatol 2002).
- Latanoprost 0.1% increased scalp hair density over 24 weeks, in a 16-man pilot (Blume-Peytavi et al., J Am Acad Dermatol 2012).
Trial results are for each drug on its own, at the strength studied, and are averages across people. The combinations here are not the products tested; no trial of the combined foam or solution was found. Compounded versions were not studied.
What this does not say
- We found no trial of these exact combinations; the evidence is for each ingredient alone.
- Tretinoin is included as a way to help other drugs penetrate the scalp; we did not find a human trial showing that effect, so we do not claim it.
- Caffeine in the 5-in-1 solution has weak evidence for hair growth in the sources we read.
- Scalp irritation and itching are the most common complaints with topical forms.
The research
behind it.
A 2026 review of tretinoin and minoxidil co-therapy in androgenetic alopecia found tretinoin enhances minoxidil's absorption and activation, improving response in some people who respond poorly to minoxidil alone.
Topical finasteride and minoxidil together outperformed either alone in a 2024 study. Tretinoin raises the chance of scalp irritation and sun sensitivity, so your physician weighs that before prescribing.
Hair loss medicines:
what the trials showFinasteride, dutasteride and minoxidil: the numbers, the time course and what the trials do not cover.Read the researchFinasteride side effects:
what the data sayTrial rates, the nocebo question, persistence after stopping, and who should not take it.Read the research
what the trials showFinasteride, dutasteride and minoxidil: the numbers, the time course and what the trials do not cover.Read the researchFinasteride side effects:
what the data sayTrial rates, the nocebo question, persistence after stopping, and who should not take it.Read the research
Getting started
takes a few minutes.
- 1
Connect with a physician
Answer a few questions online and a US-licensed physician reviews your health, history and goals to make sure treatment is right for you. 100% online. No in-person visit required.
- 2
Get your discreet shipment
If approved, your treatment is compounded by a US-licensed, LegitScript-certified pharmacy, inspected for quality, and shipped discreetly to your door.
- 3
Receive continuous support
Start with one goal, then keep building over time. Unlimited physician messaging, easy refills and dose adjustments, all from the Zepym Health app.
Frequently asked questions
Contact supportHow do I use Finasteride / Minoxidil / Tretinoin Foam, 30 mL?
Applied to the scalp, once a day, at bedtime. The starting prescription is 1 mL each time. Your physician sets your own dose and it is printed on your label.
Where do I apply it?
Thinning areas of the scalp.
What exactly is in it?
Finasteride, Minoxidil, Tretinoin.
How much arrives in each shipment?
1 bottle at the starting strength, shipped to your door from a licensed US pharmacy.
Why add tretinoin?
Some scalps convert minoxidil to its active form poorly. Tretinoin increases that conversion and helps the foam penetrate, so it is chosen for people who have not responded enough to minoxidil alone or who want the strongest topical combination. It can make the scalp more sensitive to sun and irritation; your physician decides if it fits you.
How do I apply it?
Once a day, on a dry scalp, directly to the thinning areas: dispense the foam, spread it with your fingertips, let it dry and wash your hands. Do not rinse it out. Consistency matters more than anything else.
When will I see results?
Shedding often slows by month two or three; visible thickening usually takes four to six months, and a full picture takes a year. Take photos monthly in the same light so you and your physician can compare. Individual results vary.
Can women use these foams?
Minoxidil is used for female pattern hair loss, and topical finasteride has been studied in women, but finasteride must not be used by anyone who is pregnant or may become pregnant. Your physician decides based on your history.
Finasteride / minoxidil / tretinoin foam educational content reviewed by our physician
Scott Nass, MD Doctor of Medicine, board-certified in Family Medicine
Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.
More options
in this area.
Foam
Finasteride / Minoxidil 0.25 mg / 12 mg Foam
A once-daily topical foam with finasteride and a higher 12% minoxidil for more advanced thinning or when 5% has plateaued. Prescribed by a licensed physician.
Starting at $89/mo
Capsule
Biotin / Minoxidil Capsules
Oral biotin and minoxidil to support hair growth and scalp circulation. Daily capsules for hair regrowth.
30 capsules per month
Starting at $89/mo
Solution
Dutasteride / Latanoprost / Minoxidil / Tretinoin Solution
Advanced 4-ingredient topical for maximum hair regrowth. Combines DHT blocker, vasodilator, prostaglandin, and tretinoin.
Starting at $129/mo
References
- 1.Topical finasteride for male and female pattern hair loss: is it a safe and effective alternative? J Cosmet Dermatol, 2022
- 2.Randomized trial of 5% versus 2% topical minoxidil and placebo in men with androgenetic alopecia. J Am Acad Dermatol, 2002
- 3.Long-term (5-year) multinational experience with finasteride 1 mg in men with androgenetic alopecia. Eur J Dermatol, 2002
- 4.Efficacy of combined topical minoxidil and topical finasteride compared with either alone in androgenetic alopecia. J Cosmet Dermatol, 2024
- 5.Efficacy of topical tretinoin and topical minoxidil co-therapy in androgenetic alopecia: a review. Skin Appendage Disord, 2026
Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Compounded medications are not FDA-approved brand-name products.