Zepym Health
Dutasteride / Minoxidil Solution

Applied to the scalp · Once a day

Hair lossTopicalDual DHT inhibition

Dutasteride / Minoxidil Solution

Topical dutasteride and minoxidil: stronger DHT suppression than finasteride/minoxidil, applied to the scalp with minimal systemic exposure.

  • Dutasteride blocks both DHT pathways; stronger than finasteride locally
  • Minoxidil extends growth phase on the scalp
  • Apply to dry scalp, once daily
  • Monthly$169/mo
  • Every 3 months$447 billed up front$149/mo
  • Every 6 monthsBest value$774 billed up front$129/mo
  • Free, discreet shipping
  • Licensed U.S. pharmacy
  • Board-certified physicians

Disclaimer: Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Compounded medications are not FDA-approved brand-name products.

How
Applied to the scalp
How often
Once a day
Each shipment
1 bottle
Strength
0.005 / 0.5 / 6 / 0.025%

What is topical dutasteride / minoxidil?

(dual DHT inhibitor + vasodilator solution)

Dutasteride blocks both Type I and Type II 5-alpha-reductase; topical application delivers this stronger DHT suppression to the scalp with minimal blood absorption. Combined with topical minoxidil, this solution offers more complete DHT blockade and growth stimulation for people who plateau on finasteride-based regimens.

What's in it

  • Dutasteride0.005%Stronger DHT blocker
  • Latanoprost0.5%Stimulates follicles
  • Minoxidil6%Regrows hair
  • Tretinoin0.025%Speeds skin renewal

Dual

DHT-blocking pathways in topical form; low systemic exposure

Topical dutasteride blood levels are negligible. The combination is prescribed off-label for people who need stronger local DHT suppression.

Is it right for you?

  • Who it's for

    Men who want the strongest topical formula and want to avoid pills.

  • What sets it apart

    Four actives on the scalp: dutasteride, minoxidil, latanoprost and tretinoin.

  • Worth knowing before you start

    Apply to a dry scalp at night and wash your hands. Keep it away from pregnant women.

What to expect

  • Minimal systemic effects

    topical delivery keeps side effects local

  • Hair regrowth

    new hairs visible by month 2-3

  • Scalp irritation possible

    usually mild; subsides with continued use

  • Consistent application

    daily use essential for results

How topical hair solutions work

  1. Week 1

    Apply to clean, dry scalp using the provided applicator. Many people start with once daily. Your physician monitors for irritation.

    1
  2. Week 2–4

    Scalp may shed slightly as the hair cycle resets. Do not be alarmed; this is normal and temporary.

    2
  3. Month 1–3

    Hair loss slows noticeably. New hairs begin to grow. Irritation typically subsides.

    3
  4. Month 3–6+

    Results become visible. Your physician may increase frequency or add systemic agents if needed. Maintenance is ongoing.

    4

Individual results vary. Benefits reflect what Zepym Health members commonly report to their physician at check-ins; they are not the results of a clinical trial.

How you use it

This is the starting dose the pharmacy prints on the label. Your physician sets yours and adjusts it with you.

How
Applied to the scalp
Where
thinning areas of the scalp
Dose
1 mL
How often
Once a day
When
At bedtime
Each shipment
1 bottle
Pharmacy label
Apply 1 mL to the thinning areas of the scalp once daily at bedtime for 30 days. Wash hands after use.

A sample week

  1. M
  2. T
  3. W
  4. T
  5. F
  6. S
  7. S

Once a day

The science of topical hair solutions

Topical dutasteride delivers more complete DHT suppression to the scalp than topical finasteride while avoiding systemic side effects. Combined with minoxidil, it targets follicle miniaturization from two angles.

Scalp irritation, itching, or contact dermatitis can occur. Your physician advises scalp care and monitoring. The solution should be applied to dry skin only.

Learn more

Important safety information and common side effects

Topical finasteride, dutasteride, minoxidil, tretinoin and related ingredients are applied to the scalp and minimally absorbed systemically. Local side effects include irritation, itching, contact dermatitis, and occasional hair shedding at initiation (normal hair-cycle reset). Tretinoin increases sun sensitivity, so daily sunscreen is recommended. Do not apply to broken skin or use if pregnant or breastfeeding. Wash hands after application unless treating hands. Tell your physician about any allergies to propylene glycol or other solution components, or history of sensitive scalp. Stop and seek care for severe redness, blistering, or signs of allergic reaction.

Every plan includes

  • Personalized, physician-guided plan
  • Monthly, 3-month and 6-month plans
  • Dispensed by a US-licensed compounding pharmacy
  • Unlimited protocol adjustments and messaging
  • Ongoing support and check-ins
  • Pause or cancel anytime
  • Reviewed by our in-house physicians
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How it works

  1. 1.Connect with a physician

    Answer a few questions online and a US-licensed physician reviews your health, history and goals to make sure treatment is right for you. 100% online. No in-person visit required.

  2. 2.Get your discreet shipment

    If approved, your treatment is compounded by a US-licensed, LegitScript-certified pharmacy, inspected for quality, and shipped discreetly to your door.

  3. 3.Receive continuous support

    Start with one goal, then keep building over time. Unlimited physician messaging, easy refills and dose adjustments, all from the Zepym Health app.

Topical dutasteride / minoxidil solution educational content reviewed by our physician

Scott Nass, MDDoctor of Medicine, board-certified in Family Medicine

Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.

Frequently asked questions

How do I use Dutasteride / Latanoprost / Minoxidil / Tretinoin Solution?

Applied to the scalp, once a day, at bedtime. The starting prescription is 1 mL each time. Your physician sets your own dose and it is printed on your label.

Where do I apply it?

Thinning areas of the scalp.

What exactly is in it?

Dutasteride 0.005%, Latanoprost 0.5%, Minoxidil 6%, Tretinoin 0.025%.

How much arrives in each shipment?

1 bottle at the starting strength, shipped to your door from a licensed US pharmacy.

When should I use topical dutasteride / minoxidil instead of topical finasteride / minoxidil?

If topical finasteride/minoxidil plateaus or you prefer stronger DHT suppression, your physician may trial topical dutasteride/minoxidil. Both are prescribed off-label; choice depends on response history and risk tolerance.

Why apply to dry scalp only?

Water and moisture dilute the solution, reducing its effectiveness and increasing irritation. Dry scalp ensures full-strength contact and optimal absorption.

Can I use other topical products on my scalp while using this?

Limit concurrent products. Regular shampoo is fine, but avoid other medicated scalp treatments, oils, or leave-in conditioners without your physician's approval, as they may interact.

How long before I see results?

Hair loss typically slows within 4-8 weeks. New growth becomes visible around month 2-3. Peak results occur at 6-12 months. Patience is essential.

Hair loss treated where it starts.

Ready to start?

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The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Individual results vary.

Sources

  1. 1

    Topical minoxidil and finasteride in androgenetic alopecia: efficacy and safety.

    J Clin Aesthet Dermatol, 2019
  2. 2

    Tretinoin enhancement of minoxidil response in female pattern hair loss: a systematic review.

    Dermatol Ther, 2020

from $129/mo

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