BPC-157 / KPV / TB-500

RecoveryGut & inflammation

BPC-157 / KPV / TB-500

RxPrescription onlyInjected under the skin · 5 days a week · 0.6 mg · Recovery · Gut & inflammation

Starting at $229/mo

BPC-157 and TB-500 for recovery, plus KPV, a peptide fragment studied for inflammatory signaling and gut-barrier health.

Choose your plan

Start treatment· $229/mo

Real prices from our pharmacy. Longer plans cost less per month and are billed up front. Pause or cancel anytime.

  • Recovery pair plus an anti-inflammatory peptide
  • KPV is studied for gut lining and immune balance
  • One daily injection, dosed by your physician

Every plan includes

  • Personalized, physician-guided plan
  • Monthly, 3-month and 6-month plans
  • Dispensed by a US-licensed compounding pharmacy
  • Unlimited protocol adjustments and messaging
  • Ongoing support and check-ins
  • Pause or cancel anytime
  • Reviewed by our in-house physicians
  • Physician-guided care
  • Ongoing, expert support
  • 100% online
  • Free, discreet shipping

What is BPC-157 / KPV / TB-500?

(recovery blend with KPV)

The BPC-157 and TB-500 recovery pair with KPV, the three-amino-acid tail of alpha-MSH, a natural hormone that calms inflammatory signaling. KPV has been studied mostly for gut inflammation and the gut barrier, which is why this blend is chosen when recovery and gut symptoms go together.

How it is taken
Injected under the skin
How often
5 days a week
Dose range
0.6 mg
Form
Recovery · Gut & inflammation

3-in-1

BPC-157, TB-500 and KPV in a single daily injection

Each component has preclinical evidence; the blend itself has not been studied in human trials. Prescribed off-label at your physician's discretion.

How it works,
week by week.

  1. Day 1

    A US-licensed physician reviews your injury or goal and your history and sets the dose. The kit includes everything you need.

  2. Week 1

    One small subcutaneous injection a day, usually near the area you are treating or in the abdomen. Most people find the routine easy within days.

  3. Week 2–4

    Repair signaling builds. Many people report less soreness and easier movement first; structural healing takes longer.

  4. 2–3 Months

    A typical protocol runs 4 to 12 weeks. Your physician checks progress and decides whether to continue, pause or adjust.

  5. Beyond

    Peptides support recovery; load management, sleep and nutrition do the rest. Your physician helps you plan the next block if you need one.

What you may notice,
and when.

  • Faster recovery

    less downtime between hard sessions

  • Tendons and joints

    the most common reason members start

  • Gut comfort

    reported most with the KPV and BPC-157 blends

  • Skin and tissue

    reported most with the GHK-Cu blends

Individual results vary. Benefits reflect what Zepym Health members commonly report to their physician at check-ins; they are not the results of a clinical trial.

Safety first:
what to know before you start.

Important safety information and common side effects

Recovery peptides are generally well tolerated. The most common effects are mild: redness, itching or a small bump at the injection site, headache, flushing or nausea in the first days. Because these peptides support cell growth and blood-vessel formation, they are not prescribed with an active cancer, a cancer under evaluation, or during pregnancy or breastfeeding. GHK-Cu contains copper: tell your physician about Wilson's disease or copper sensitivity. Stop and seek care for hives, swelling of the face or lips or trouble breathing. Tell your physician about every medication you take.

The research behind
BPC-157.

A 15-amino-acid peptide from a gastric protein. Almost all of the evidence is from rodent and other animal studies; human data are a handful of small, uncontrolled reports.

About the added ingredient: TB-500 is a fragment of thymosin beta-4. Its human data are extremely limited; most of the published work is in animals, not controlled human trials.

What the studies found

  • No benefit has been shown in people. Animal studies of tendon cuts, muscle crush and bone fracture report faster healing (review, PMC 2025).
  • The only human data are three pilot studies without a controlled efficacy outcome, so no human benefit is established (review, PMC 2025).
  • Cell and animal work reports protective effects on the stomach lining, gut and blood vessels after injury; these are unproven in people (2026 review of BPC-157).

No published human study has measured how BPC-157 behaves in people at the doses sold here. Research-grade and compounded versions were not the ones studied in animals or in the few human reports.

What this does not say

  • No controlled human trial shows that BPC-157 heals tendons, muscles, bone or gut tissue.
  • FDA's list of bulk drug substances that may present significant safety risks describes compounded BPC-157 as carrying immunogenicity risk, with limited safety data for the proposed routes. The entry is among withdrawn nominations and the compounding rules have changed, so check the FDA page before relying on it.
  • The brand products are not the compounded versions described by FDA and the reviews. Oral capsules were not studied in people.

The research
behind it.

KPV reduced inflammatory signaling and protected the gut lining in preclinical colitis models, and is being studied in targeted delivery systems for that reason.

BPC-157 and TB-500 bring the tissue-repair evidence. Your physician decides whether the added KPV fits your history.

Getting started
takes a few minutes.

  1. 1

    Connect with a physician

    Answer a few questions online and a US-licensed physician reviews your health, history and goals to make sure treatment is right for you. 100% online. No in-person visit required.

  2. 2

    Get your discreet shipment

    If approved, your treatment is compounded by a US-licensed, LegitScript-certified pharmacy, inspected for quality, and shipped discreetly to your door.

  3. 3

    Receive continuous support

    Start with one goal, then keep building over time. Unlimited physician messaging, easy refills and dose adjustments, all from the Zepym Health app.

Start treatment

Frequently asked questions

Contact support
How do I use BPC-157 / KPV / TB-500?

Injected under the skin, 5 days a week, in the morning. The starting prescription is 20 units (0.6 mg) each time. Your physician sets your own dose and it is printed on your label.

What exactly is in it?

BPC-157, KPV, TB-500.

How much arrives in each shipment?

1 vial at the starting strength, shipped to your door from a licensed US pharmacy.

What does KPV add?

KPV is a small peptide fragment studied for calming inflammatory signaling and supporting the gut barrier. It is added when recovery goals come with gut or inflammation complaints. Your physician decides whether it is right for you.

How do I take it?

A small subcutaneous injection once a day with an insulin-style needle, usually in the abdomen or near the area you are treating. Your physician sets the dose and the length of the protocol; the kit includes everything.

What are the side effects?

Mild and local for most people: redness, itching or a small bump where you inject, and occasionally headache, flushing or nausea in the first days. These peptides are not prescribed with an active or suspected cancer or in pregnancy. Read the safety information above.

How strong is the evidence?

Honest answer: early. There is decades of preclinical research and clinical experience, but few controlled human trials. Your physician explains that before prescribing, and these peptides are prescribed off-label at their discretion.

BPC-157 / KPV / TB-500 educational content reviewed by our physician

Scott Nass, MD Doctor of Medicine, board-certified in Family Medicine

Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.

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References

  1. 1.Review of BPC-157 in tissue repair and pain management: mechanisms and the state of the evidence. Int J Mol Sci, 2026
  2. 2.Review of peptide therapy for tendon, ligament and muscle injury, including BPC-157. Pharmaceuticals (Basel), 2026
  3. 3.BPC-157 and TB-500 improved Achilles tendon healing on histological and biomechanical measures in a rat model. Jt Dis Relat Surg, 2026
  4. 4.Thymosin beta-4 (the parent of TB-500): the journey from laboratory to human trials in eye repair. Expert Opin Biol Ther, 2018
  5. 5.Topically applied GHK-Cu as an anti-aging peptide: advantages, problems and prospects. Bioimpacts, 2025

Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Compounded medications are not FDA-approved brand-name products.