Tirzepatide + B12
A weekly dual-action GLP-1/GIP injection for meaningful weight loss and appetite control, paired with vitamin B12 for energy.
Injection
from $208/mo
Injected under the skin · Once a week
Weight lossGLP-1Injection
Semaglutide + L-Carnitine
Weekly semaglutide injection combined with L-carnitine to support energy metabolism and mitochondrial function during weight loss. Both components support the body's ability to burn fat.
- GLP-1 for appetite regulation and weight loss
- L-carnitine supports energy and fat metabolism
- Once-weekly injection; compounded together
- Monthly$279/mo
- Every 3 months$497 billed up front$166/mo
- Every 6 monthsBest value$774 billed up front$129/mo
- Free, discreet shipping
- Licensed U.S. pharmacy
- Board-certified physicians
Disclaimer: Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Compounded medications are not FDA-approved brand-name products.
- How
- Injected under the skin
- How often
- Once a week
- Each shipment
- 1 vial
- Strengths
- 4 options · 0.75–2.5 mg semaglutide
What is Semaglutide + L-Carnitine?
(GLP-1 plus amino acid metabolite)
L-carnitine is an amino acid metabolite that transports fatty acids into mitochondria for energy production. Pairing semaglutide (GLP-1) with L-carnitine supports appetite control while providing the nutritional support to maintain energy during calorie reduction and fat burning.
What's in it
- SemaglutideGLP-1: quiets appetite, slows digestion
- L-CarnitineCarries fat into the cell to be burned
Combined
GLP-1 for weight loss, L-carnitine for energy support
Semaglutide reduces appetite; L-carnitine supports the metabolism of fat for fuel. The combination targets both hunger and energy, a common concern during weight loss. Your physician adjusts both doses based on your response.
Is it right for you?
Who it's for
People on semaglutide who feel flat or low on energy during a calorie deficit.
What sets it apart
L-carnitine carries fat into the cell to be burned; in trials on its own it adds a small amount of weight loss.
Worth knowing before you start
A fishy body odor can appear with carnitine. It is harmless; tell your physician if it bothers you.
Results you can feel
Weight loss
steady with semaglutide appetite control
Energy and stamina
supported by B12, L-carnitine, or methylcobalamin
Better sleep
glycine improves sleep quality from week one
Comfort
additives smooth the first weeks of weight loss
How combination weight loss works
Day 1
A US-licensed physician reviews your goals and health. Explains how semaglutide works and what each additive (energy, sleep, metabolism) brings to your plan.
1Week 1
First injection. Appetite often quiets within days. Additives (B12, glycine, L-carnitine) begin supporting your energy and recovery.
2Weeks 2–4
Fullness comes sooner, cravings soften. Energy and sleep improve as the additives settle in. Your physician checks in before any dose adjustment.
3Months 2–3
Weight loss builds steadily. Additive benefits (sustained energy, better sleep, muscle support) help you feel good while losing weight.
4Beyond
Maintenance: your physician adjusts doses to hold your results. Long-term use of additives supports sustained energy and health.
5
Individual results vary. Benefits reflect what Zepym Health members commonly report to their physician at check-ins; they are not the results of a clinical trial.
How you use it
This is the starting dose the pharmacy prints on the label. Your physician sets yours and adjusts it with you.
- How
- Injected under the skin
- Dose
- 7.5 units (0.75 mg semaglutide)
- How often
- Once a week
- Each shipment
- 1 vial
- Pharmacy label
- Inject 7.5 units (0.75 mg semaglutide) subcutaneously once weekly for 4 weeks. Discard any remaining medication.
A sample week
- M
- T
- W
- T
- F
- S
- S
Once a week
Strengths the pharmacy carries
- 4 mg / 200 mg (2 mg / 100 mg/mL)
- 3 mg / 300 mg (1 mg / 100 mg/mL)
- 10 mg / 200 mg (5 mg / 100 mg/mL)
- 8 mg / 400 mg (2 mg / 100 mg/mL)
The science of combination therapy
GLP-1 injection is well-studied for weight loss. L-carnitine is a natural compound that improves muscle energy and fat oxidation in exercise and metabolic studies.
Together, they target appetite (semaglutide) and energy (L-carnitine), addressing two common challenges during weight loss. Individual response varies.
Learn moreImportant safety information and common side effects
Semaglutide plus additives carries the safety profile of semaglutide itself: nausea, vomiting, diarrhea, constipation, reduced appetite, fatigue, and injection-site reactions are common in early weeks. The additives (L-carnitine, methylcobalamin, glycine) are generally well-tolerated. Do not use with medullary thyroid carcinoma history or MEN 2. Not for pregnancy or breastfeeding, or with active pancreatitis. Tell your physician about all medications, diabetes drugs, and any kidney or pancreatic disease. Stop and seek care for severe abdominal pain, allergic reactions, or signs of pancreatitis.
Every plan includes
- Personalized, physician-guided plan
- Monthly, 3-month and 6-month plans
- Dispensed by a US-licensed compounding pharmacy
- Unlimited protocol adjustments and messaging
- Ongoing support and check-ins
- Pause or cancel anytime
- Reviewed by our in-house physicians
How it works
1.Connect with a physician
Answer a few questions online and a US-licensed physician reviews your health, history and goals to make sure treatment is right for you. 100% online. No in-person visit required.
2.Get your discreet shipment
If approved, your treatment is compounded by a US-licensed, LegitScript-certified pharmacy, inspected for quality, and shipped discreetly to your door.
3.Receive continuous support
Start with one goal, then keep building over time. Unlimited physician messaging, easy refills and dose adjustments, all from the Zepym Health app.
Semaglutide + L-Carnitine educational content reviewed by our physician
Scott Nass, MDDoctor of Medicine, board-certified in Family Medicine
Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.
Frequently asked questions
How do I use Semaglutide + L-Carnitine?
Injected under the skin, once a week. The starting prescription is 7.5 units (0.75 mg semaglutide) each time. Your physician sets your own dose and it is printed on your label.
What strengths does Semaglutide + L-Carnitine come in?
The pharmacy carries 4: 3 mg / 300 mg (1 mg / 100 mg/mL), 4 mg / 200 mg (2 mg / 100 mg/mL), 8 mg / 400 mg (2 mg / 100 mg/mL), 10 mg / 200 mg (5 mg / 100 mg/mL). Your physician chooses which one you get.
What exactly is in it?
Semaglutide, L-Carnitine.
How much arrives in each shipment?
1 vial at the starting strength, shipped to your door from a licensed US pharmacy.
Does L-carnitine help with weight loss?
L-carnitine supports fat metabolism and energy production, not appetite. When combined with semaglutide, it may help you maintain energy while losing weight. Effects are modest and depend on diet and activity.
Do I need all three additives?
Not necessarily. Your physician will suggest the combination that matches your needs. If fatigue is your main concern, B12 and L-carnitine help. If sleep is the issue, glycine is the focus. You can change your combination over time.
Are additives safe long-term?
Yes. B12, glycine, and L-carnitine are natural compounds your body uses daily. They are safe at the doses used here, even for years of use. Your physician monitors you at regular check-ins.
What if additives don't help?
Some people feel a difference immediately; others take weeks. If you don't notice energy or sleep improvements after 4–6 weeks, your physician may adjust doses or try a different additive combination.
Semaglutide with nutrients for better results.
Semaglutide + B12
A weekly GLP-1 injection that quiets cravings and supports steady, sustainable weight loss, paired with vitamin B12 for energy.
Injection
from $129/mo
Tirzepatide + Glycine
A weekly dual-action GLP-1/GIP injection for meaningful weight loss and appetite control, paired with glycine for better tolerance.
Injection
from $208/mo
Semaglutide + Glycine
A weekly GLP-1 injection that quiets cravings and supports steady, sustainable weight loss, paired with glycine for better tolerance.
Injection
from $129/mo
The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Individual results vary.
Sources
- 1
Semaglutide for weight loss (STEP 1): once-weekly GLP-1 resulted in mean 15% weight loss over 68 weeks.
NEJM, 2021 (Wilding JPH et al.) - 2
L-carnitine supplementation improves energy metabolism and exercise performance in metabolic studies.
Nutrients, 2021 (Malaguarnera M)
Semaglutide + L-Carnitinefrom $129/mo