GLP-1 + GIP
Tirzepatide for weight loss
Compounded tirzepatide, prescribed online by a U.S.-licensed physician who sets your dose and adjusts it with you. As a weekly injection or a daily tablet that dissolves under the tongue.
- Acts on two appetite hormones, GLP-1 and GIP
- 20.9% average weight loss at 72 weeks in the SURMOUNT-1 trial (15 mg)
- Medication, physician care and shipping in one monthly price
Tirzepatidefrom $208/mo
- Free, discreet shipping
- Licensed U.S. pharmacies
- U.S.-licensed physicians
Compounded medications are not FDA-approved. A physician decides whether tirzepatide is right for you.
How tirzepatide works
Two hormones, not one
Tirzepatide acts on the receptors of two gut hormones, GLP-1 and GIP. Semaglutide acts only on GLP-1.
Less hunger, full sooner
It slows how fast the stomach empties and signals fullness to the brain, so smaller meals feel like enough.
It steps up slowly
The weekly dose starts at 2.5 mg and rises every 4 weeks, as your physician decides, up to 15 mg.
What the trials showed
In SURMOUNT-1, 2,539 adults with obesity or overweight took weekly tirzepatide or placebo for 72 weeks, with diet and exercise.
In SURMOUNT-5, tirzepatide led to 20.2% average weight loss at 72 weeks, against 13.7% with semaglutide.
These trials used brand-name tirzepatide. Compounded tirzepatide was not studied in them, and individual results vary.
SURMOUNT-1: Jastreboff AM et al. N Engl J Med, 2022. SURMOUNT-5: Aronne LJ et al. N Engl J Med, 2025.
Our tirzepatide options
Six forms, all prepared by licensed U.S. pharmacies. Your physician recommends one with you.
Weekly injection
Tirzepatide + B12
A weekly dual-action GLP-1/GIP injection for meaningful weight loss and appetite control, paired with vitamin B12 for energy.
From $208/mo
See details Tirzepatide + B12Weekly injection
Tirzepatide + Glycine
A weekly dual-action GLP-1/GIP injection for meaningful weight loss and appetite control, paired with glycine for better tolerance.
From $208/mo
See details Tirzepatide + GlycineWeekly injection
Tirzepatide + B6
Tirzepatide with vitamin B6 for enhanced weight loss and energy. Weekly injection, 10 mg/mL solution. Escalating six-tier ladder.
From $208/mo
See details Tirzepatide + B6Weekly injection
Tirzepatide + Glycine + Methylcobalamin
Tirzepatide with glycine and methylcobalamin for weight loss with recovery and energy. Weekly injection, five-tier ladder.
From $208/mo
See details Tirzepatide + Glycine + MethylcobalaminWeekly injection
Tirzepatide + L-Carnitine
Tirzepatide with L-Carnitine for weight loss and fat mobilization. Weekly injection, escalating three-tier system.
From $208/mo
See details Tirzepatide + L-CarnitineDaily tablet
Tirzepatide ODT
Tirzepatide oral dissolving tablet. Dual GIP/GLP-1 agonist for weight loss. Escalating dose titration protocol.
From $289/mo
See details Tirzepatide ODT
How it's taken
Weekly injection
- 2.5 mg
- 5 mg
- 7.5 mg
- 10 mg
- 12.5 mg
- 15 mg
A small injection under the skin once a week. Each step lasts 4 weeks, as on the pharmacy label; your physician decides when to go up.
Daily dissolving tablet
One tablet under the tongue once a day, 30 minutes before food or drink. Strengths from 3 mg to 12 mg, set by your physician.
Compounded tirzepatide vs. Zepbound®
Both contain tirzepatide. They are not the same product, and we only offer the compounded one.
| Compounded tirzepatide | Zepbound® | |
|---|---|---|
| Active ingredient | Tirzepatide | Tirzepatide |
| Who makes it | A licensed U.S. compounding pharmacy, for you, under your prescription | Eli Lilly and Company |
| FDA approval | Not FDA-approved | FDA-approved |
| Forms | Weekly injection (vial), some with B12, B6, glycine or L-carnitine; or a daily dissolving tablet | Weekly injection (pen or vial) |
| How you pay | Cash pay, one monthly price with your physician and shipping | Insurance, if your plan covers it, or the manufacturer's price |
| At Zepym Health | Yes | No, we don't offer Zepbound® |
Zepbound® and Mounjaro® are registered trademarks of Eli Lilly and Company. Zepym Health is not affiliated with or endorsed by Eli Lilly.
Side effects and safety
Most common
- Nausea, diarrhea, vomiting or constipation, mostly while the dose steps up
- Decreased appetite, indigestion and stomach pain
- Injection-site reactions
Less common but serious
- Pancreatitis
- Gallbladder problems
- Low blood sugar, especially with insulin or sulfonylureas
- Kidney problems from dehydration
Not for you if
- You or your family have had medullary thyroid cancer or MEN 2 (thyroid C-cell tumors were seen in rodents)
- You are pregnant, trying to get pregnant or breastfeeding
- You have had pancreatitis
Tirzepatide questions
Contact supportIs compounded tirzepatide the same as Zepbound?
Both contain tirzepatide, but they are different products. Zepbound is FDA-approved and made by Eli Lilly. Compounded tirzepatide is prepared by a licensed U.S. pharmacy for you under a prescription and is not FDA-approved. We don't offer Zepbound.
How much weight can I lose with tirzepatide?
In the SURMOUNT-1 trial, adults on 15 mg lost 20.9% of their body weight on average at 72 weeks, against 3.1% with placebo. Results vary from person to person, and compounded tirzepatide was not studied in that trial.
How much does tirzepatide cost?
Each option shows its current monthly price on this page and on its own page. The price includes your physician, the medication and shipping, and longer plans cost less per month. No insurance is needed.
Tirzepatide or semaglutide?
Tirzepatide acts on GLP-1 and GIP; semaglutide on GLP-1 only. In the SURMOUNT-5 trial, tirzepatide led to more weight loss at 72 weeks (20.2% against 13.7%). Your physician recommends one based on your health and history.
Who can take tirzepatide?
Generally adults with a BMI of 30 or more, or 27 or more with a weight-related condition such as high blood pressure or type 2 diabetes. A physician licensed in your state reviews your answers and decides.
Is tirzepatide an injection?
Usually, once a week under the skin. We also offer a tablet that dissolves under the tongue once a day for people who prefer not to inject.
How do I get tirzepatide online?
Answer a few health questions online. A U.S.-licensed physician reviews them; if tirzepatide is right for you, a licensed pharmacy prepares it and ships it to your door.
Start with a physician, not a guess.
Answer a few questions online. A U.S.-licensed physician reviews them and, if tirzepatide is right for you, it ships to your door.
Get started
Compounded medications are not approved or evaluated for safety, efficacy, or quality by the FDA.