RecoveryConnective tissue
TB-500

TB-500

Rx

A peptide studied for cell migration and tissue-repair signaling, used to support recovery of muscle and connective tissue.

  • Studied for muscle and connective-tissue recovery
  • Supports the cell migration that repair depends on
  • Subcutaneous injection, dosed by your physician
  • Monthly and 3-month plans
  • Starting price applies to the 3-month plan
  • US-licensed pharmacies
  • Pause or cancel anytime

Starting at

$189 / mo

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  • Physician-guided care
  • Ongoing, expert support
  • 100% online
  • Free, discreet shipping

Disclaimer

Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Compounded medications are not FDA-approved brand-name products.

What is TB-500?

(a fragment of thymosin beta-4)

TB-500 is a synthetic version of the active region of thymosin beta-4, a 43-amino-acid protein your body makes to organize actin, the scaffolding cells use to move. That movement is what lets repair cells reach an injury, which is why thymosin beta-4 has been studied in wound, heart and eye healing.

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thymosin beta-4, the natural protein TB-500 is derived from

43 aa

Thymosin beta-4 has been studied in human trials for eye and wound healing; TB-500 itself is prescribed off-label at your physician's discretion.

How recovery peptides work

  1. Day 1

    A US-licensed physician reviews your injury or goal and your history and sets the dose. The kit includes everything you need.

  2. Week 1

    One small subcutaneous injection a day, usually near the area you are treating or in the abdomen. Most people find the routine easy within days.

  3. Week 2–4

    Repair signaling builds. Many people report less soreness and easier movement first; structural healing takes longer.

  4. 2–3 Months

    A typical protocol runs 4 to 12 weeks. Your physician checks progress and decides whether to continue, pause or adjust.

  5. Beyond

    Peptides support recovery; load management, sleep and nutrition do the rest. Your physician helps you plan the next block if you need one.

Results you can feel

RecoveryLess soreness
  • Faster recovery

    less downtime between hard sessions

  • Tendons and joints

    the most common reason members start

  • Gut comfort

    reported most with the KPV and BPC-157 blends

  • Skin and tissue

    reported most with the GHK-Cu blends

Individual results vary. Benefits reflect what Zepym Health members commonly report to their physician at check-ins; they are not the results of a clinical trial.

Tested for quality, backed by science

We only work with US-licensed pharmacies that prioritize strict quality control standards, so you can count on purity, potency, and safety.

  • Pure: compounded to order with pharmaceutical-grade ingredients
  • Potent: lab-tested to match the labeled dose
  • Sterile: prepared to USP standards by LegitScript-certified pharmacies

Your plan, reviewed

Physician-reviewed

Dose set by a physician, adjusted at every check-in

Scott Nass, MD

Your reviewing physician

Scott Nass, MD

Board-certified family physician. Every recovery peptide plan at Zepym Health is reviewed by a licensed physician before anything is prescribed, and adjusted with you as you go.

Meet the team

What the research says

The science of recovery peptides

Thymosin beta-4 promotes cell migration, blood-vessel growth and reduced inflammation in injured tissue, and has reached human trials in eye and skin wound healing.

For muscle and tendon recovery the evidence is preclinical. Your physician sets the dose and follows how you respond at check-ins.

Learn more

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Recovery care that starts with you

Our in-house physicians meet you where you are, and get you to where you want to be.

$189/ mo

Applies to the 3-month plan billed in full ($189/mo on the monthly plan)

What's included

  • Personalized, physician-guided plan
  • Monthly and 3-month plans
  • Dispensed by a US-licensed compounding pharmacy
  • Unlimited protocol adjustments and messaging
  • Ongoing support and check-ins
  • Pause or cancel anytime
  • Reviewed by our in-house physicians
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Personalized for you

Made for your biology

No two people age the same way, so no two treatments are exactly the same. Your plan is guided by your symptoms, your biology, and your priorities. It's a whole “you” approach to living a better, longer life.

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How it works

Choosing how you age starts here

  1. Physician-led

    Connect with a physician

    Answer a few questions online and a US-licensed physician reviews your health, history and goals to make sure treatment is right for you. 100% online. No in-person visit required.

  2. Fast, discreet shipping

    Get your discreet shipment

    If approved, your treatment is compounded by a US-licensed, LegitScript-certified pharmacy, inspected for quality, and shipped discreetly to your door.

  3. 100% online

    Receive continuous support

    Start with one goal, then keep building over time. Unlimited physician messaging, easy refills and dose adjustments, all from the Zepym Health app.

Disclaimer

The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Individual results vary.

TB-500 educational content reviewed by our physician

Scott Nass, MD

Scott Nass, MD

Doctor of Medicine, board-certified in Family Medicine

Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.

Frequently asked questions

Ready to start?

Answer a few questions and take your first step to living well.

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Have more questions?

We're here to help you get where you need to be.

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May the source be with you.

We read the research so you don't have to. Here's what the science says.

  1. 1

    Review of BPC-157 in tissue repair and pain management: mechanisms and the state of the evidence.

    Int J Mol Sci, 2026
  2. 2

    Review of peptide therapy for tendon, ligament and muscle injury, including BPC-157.

    Pharmaceuticals (Basel), 2026
  3. 3

    BPC-157 and TB-500 improved Achilles tendon healing on histological and biomechanical measures in a rat model.

    Jt Dis Relat Surg, 2026
  4. 4

    Thymosin beta-4 (the parent of TB-500): the journey from laboratory to human trials in eye repair.

    Expert Opin Biol Ther, 2018
  5. 5

    Topically applied GHK-Cu as an anti-aging peptide: advantages, problems and prospects.

    Bioimpacts, 2025

Starting at $189 / mo

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