Estradiol Cypionate
Long-acting estradiol injection for menopause and perimenopause symptoms and for gender-affirming hormone therapy, given every one to two weeks. Prescribed and dosed by a licensed physician.
Injection
from $139/mo
Injected into the muscle · Once a week
TestosteroneInjectableLong-acting
Testosterone Enanthate (Grapeseed Oil)
Compounded testosterone enanthate 250 mg/mL in grapeseed oil: long-acting ester, injected weekly or biweekly. Slightly longer half-life than cypionate; steady testosterone replacement.
- Slightly longer half-life than cypionate (7–8 days)
- Weekly or biweekly injection, steady levels
- Compounded in natural grapeseed oil
- Monthly$199/mo
- Every 3 months$447 billed up front$149/mo
- Every 6 monthsBest value$594 billed up front$99/mo
- Free, discreet shipping
- Licensed U.S. pharmacy
- Board-certified physicians
Disclaimer: Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Compounded medications are not FDA-approved brand-name products.
- How
- Injected into the muscle
- How often
- Once a week
- Each shipment
- 1 vial
- Strength
- 200 mg/mL
What is testosterone enanthate?
(en-ANN-thate)
Testosterone enanthate is testosterone with an enanthate ester (slightly longer than cypionate), dissolved in grapeseed oil. Half-life is about 7–8 days, slightly longer than cypionate (7 days), meaning slightly flatter levels between injections. Typical dose: 100–250 mg weekly or biweekly. Compounded formulations allow customization.
What's in it
- Testosterone EnanthateReplaces low testosterone
Compounded
longer ester; slightly flatter kinetics; weekly or biweekly injection
Testosterone enanthate provides very steady levels due to its slightly longer half-life. Some men prefer it over cypionate for smoother levels. Compounded formulations may vary in potency.
Is it right for you?
Who it's for
Men who prefer enanthate and want a thin oil.
What sets it apart
Enanthate leaves the body slightly faster than cypionate; in practice the two are used the same way.
Worth knowing before you start
If cypionate caused pain or a reaction at the site, switching ester and oil is a reasonable try.
What to expect
Sustained energy and libido
steady testosterone supports mood and sexual function
Improved muscle and strength
testosterone builds lean mass over 4–12 weeks
Lab-monitored
hematocrit, PSA, BP, lipids tracked regularly
Home injection
self-injection at home once or twice weekly
How injectable testosterone works
Day 1
US-licensed physician reviews testosterone goals, medical history, and baseline labs (testosterone, hematocrit, PSA, lipids, BP).
1Week 1
Teach injection technique. Start testosterone injection (weekly or biweekly). Most men learn to self-inject at home in minutes.
2Week 4
Blood work checks testosterone level. If low, dose is increased. If target is reached, dose is maintained.
3Month 2–3
Follow-up labs (testosterone, hematocrit, PSA, lipids, BP). Symptoms (energy, mood, libido, strength) reviewed.
4Beyond
Testosterone monitored every 3–6 months; hematocrit and PSA every 6–12 months; BP every 3–6 months. Dose adjusted to keep testosterone in target range.
5
Individual results vary. Benefits reflect what Zepym Health members commonly report to their physician at check-ins; they are not the results of a clinical trial.
How you use it
This is the starting dose the pharmacy prints on the label. Your physician sets yours and adjusts it with you.
- How
- Injected into the muscle
- Dose
- 0.5 mL (100 mg)
- How often
- Once a week
- Each shipment
- 1 vial
- Pharmacy label
- Inject 0.5 mL (100 mg) intramuscularly once weekly for 4 weeks. Discard any remaining medication.
A sample week
- M
- T
- W
- T
- F
- S
- S
Once a week
The science of injectable testosterone
Testosterone enanthate has a slightly longer half-life than cypionate (7–8 days vs. 7 days), resulting in marginally flatter testosterone curves between injections.
The difference between enanthate and cypionate is clinically subtle but some men report better stability on enanthate.
Learn moreImportant safety information and common side effects
Injectable testosterone (cypionate, enanthate) carries the same safety profile as all testosterone therapy: elevated hematocrit (polycythemia), blood pressure elevation, PSA increase, reduced fertility during therapy, and clotting concerns. Polycythemia (high red cell count) is monitored with hematocrit tests every 6–12 months; if hematocrit rises above 54%, testosterone is held or reduced. PSA is checked at baseline and annually. Blood pressure is monitored every 3–6 months. Tell your physician about high blood pressure, blood clotting disorders, prostate cancer concerns, or fertility plans. Common injection-site reactions are mild (redness, soreness) and resolve in days. Stop and seek care for chest pain, shortness of breath, leg swelling, severe injection-site reactions, or signs of stroke.
Every plan includes
- Personalized, physician-guided plan
- Monthly, 3-month and 6-month plans
- Dispensed by a US-licensed compounding pharmacy
- Unlimited protocol adjustments and messaging
- Ongoing support and check-ins
- Pause or cancel anytime
- Reviewed by our in-house physicians
How it works
1.Connect with a physician
Answer a few questions online and a US-licensed physician reviews your health, history and goals to make sure treatment is right for you. 100% online. No in-person visit required.
2.Get your discreet shipment
If approved, your treatment is compounded by a US-licensed, LegitScript-certified pharmacy, inspected for quality, and shipped discreetly to your door.
3.Receive continuous support
Start with one goal, then keep building over time. Unlimited physician messaging, easy refills and dose adjustments, all from the Zepym Health app.
Testosterone enanthate (grapeseed oil) educational content reviewed by our physician
Scott Nass, MDDoctor of Medicine, board-certified in Family Medicine
Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.
Frequently asked questions
How do I use Testosterone Enanthate (GSO)?
Injected into the muscle, once a week. The starting prescription is 0.5 mL (100 mg) each time. Your physician sets your own dose and it is printed on your label.
How much arrives in each shipment?
1 vial at the starting strength, shipped to your door from a licensed US pharmacy.
Is it a controlled substance?
Yes. The law requires a live video visit with the physician before it can be prescribed.
Should I use enanthate or cypionate?
Both are effective and widely used. Cypionate is more common; enanthate has a slightly longer half-life for marginally flatter levels. Your physician may recommend one based on your preference or response. Both require weekly or biweekly injections.
How do I inject testosterone?
Your physician or nurse teaches you the technique in the first visit. Most men learn subcutaneous (under the skin) injection in seconds and feel comfortable within days. Intramuscular injection (into muscle) is also an option. Injections are done at home, typically once or twice per week.
What if my hematocrit rises?
Hematocrit (red blood cell count) can rise on testosterone. If it exceeds 54%, your physician may reduce your testosterone dose, have you donate blood, or pause therapy until it normalizes. Monitor hematocrit every 6–12 months.
Will testosterone affect my fertility?
Exogenous testosterone suppresses your body's natural testosterone production (testicular shutdown) and reduces sperm production. This is reversible: within 3–12 months of stopping testosterone, fertility usually returns. To preserve fertility during therapy, your physician may prescribe clomiphene or hCG alongside testosterone.
How long until I feel effects?
Many men notice improved energy, mood, and libido within 2–4 weeks. Muscle and strength gains take 4–12 weeks. Erectile function often improves within 2–8 weeks.
Testosterone replacement via weekly or biweekly injection.
Gonadorelin
A copy of the brain's own GnRH signal that keeps the testes producing testosterone and sperm, used alongside testosterone therapy and in fertility care. Prescribed and dosed by a licensed physician.
Injection
from $159/mo
7-Keto DHEA Capsules
7-Keto DHEA, a metabolite of DHEA that does not convert to testosterone or estrogen. Supports energy and metabolism without hormonal side effects.
Capsule
from $79/mo
Anastrozole - Men
A low-dose aromatase inhibitor for men on testosterone therapy whose blood work shows high estradiol, easing breast tenderness and water retention. Slow-release capsule, prescribed and dosed by a licensed physician.
Capsule
from $54/mo
The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Individual results vary.
Sources
- 1
Endocrine Society Clinical Practice Guidelines for testosterone therapy: dosing, monitoring, and complications.
J Clin Endocrinol Metab, 2018 - 2
TRAVERSE trial: testosterone replacement and cardiovascular outcomes in hypogonadal men.
N Engl J Med, 2021
Testosterone Enanthate (Grapeseed Oil)from $99/mo