Zepym Health
Sildenafil + Tadalafil + Vardenafil Drops

Dissolved under the tongue · Once a day

Sexual healthCombinationSublingual

Sildenafil + Tadalafil + Vardenafil Drops

Single-use sublingual ampules combining low doses of three PDE5 inhibitors, taken once daily to keep a steady baseline of erectile readiness.

  • Daily ampule, no timing around sex
  • Low doses of three agents rather than a high dose of one
  • Held under the tongue, then swallowed
  • Monthly$179/mo
  • Every 3 months$477 billed up front$159/mo
  • Every 6 monthsBest value$834 billed up front$139/mo
  • Free, discreet shipping
  • Licensed U.S. pharmacy
  • Board-certified physicians

Disclaimer: Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Compounded medications are not FDA-approved brand-name products.

How
Dissolved under the tongue
How often
Once a day
Each shipment
1 bottle
Strengths
2 options

What are the triple drops?

(sublingual emulsion)

Each ampule holds a small dose of sildenafil, tadalafil and vardenafil in an emulsion absorbed under the tongue. The goal is steady daily support, similar to daily low-dose tadalafil.

What's in it

  • SildenafilPDE5 inhibitor: blood flow, about 4 hours
  • TadalafilPDE5 inhibitor: blood flow, up to 36 hours
  • VardenafilPDE5 inhibitor: fast onset

30

single-use ampules per box, one a day

Compounded combination; no trials of this exact product.

Is it right for you?

  • Who it's for

    Men who want a daily low dose of three medicines instead of one before sex.

  • What sets it apart

    The only daily-use combination here: an ampule under the tongue every day.

  • Worth knowing before you start

    Because it is daily, never add another ED pill on top.

Results you can rely on

  • Firmer erections

    when aroused, with a reliable response

  • Predictable timing

    you know when it starts and how long it lasts

  • Confidence

    less performance worry, more presence

  • Physician oversight

    dose and form adjusted to you

How combination therapy works

  1. Day 1

    A US-licensed physician reviews your health, medications (especially nitrates and blood pressure drugs) and goals, and chooses the dose and form.

    1
  2. First doses

    Take it 20 to 30 minutes before intimacy, on a light stomach. Arousal is still needed; the medicine helps the response, it does not create it.

    2
  3. Week 2

    You know how your body responds. Timing, dose and food effects are clear, and confidence builds.

    3
  4. Month 1

    Check-in with your physician: the dose is adjusted up or down, or the form is changed, based on your response and side effects.

    4
  5. Beyond

    It works for as long as you use it. Your physician reviews your health at least yearly, including blood pressure and heart health.

    5

Individual results vary. Benefits reflect what Zepym Health members commonly report to their physician at check-ins; they are not the results of a clinical trial.

How you use it

This is the starting dose the pharmacy prints on the label. Your physician sets yours and adjusts it with you.

How
Dissolved under the tongue
Dose
one ampule
How often
Once a day
Each shipment
1 bottle
Pharmacy label
Empty one ampule under the tongue once daily. Hold for 1 minute, then swallow, and do not eat or drink for 5 minutes. Use for 30 days.

A sample week

  1. M
  2. T
  3. W
  4. T
  5. F
  6. S
  7. S

Once a day

Strengths the pharmacy carries

  • 40 mg / 4 mg / 15 mg
  • 25 mg / 5 mg / 7.5 mg

The science of combination therapy

Daily low-dose PDE5 therapy is well studied with tadalafil; this product applies the idea with three agents at low doses.

Side effects are those of PDE5 inhibitors. Your physician reviews your blood pressure and medications before starting.

Learn more

Important safety information and common side effects

PDE5 inhibitors are generally well tolerated. Common effects are flushing, headache, nasal congestion, indigestion and, with sildenafil, a temporary blue tint to vision. CRITICAL: never combine with nitrates or poppers (dangerous drop in blood pressure). Use with care alongside alpha-blockers. Seek emergency care for an erection lasting more than 4 hours, sudden vision or hearing loss, or chest pain. Tell your physician about heart disease, low blood pressure, liver or kidney problems and retinal disease before starting. Apomorphine adds nausea, yawning, dizziness and drowsiness; avoid driving until you know how you react.

Every plan includes

  • Personalized, physician-guided plan
  • Monthly, 3-month and 6-month plans
  • Dispensed by a US-licensed compounding pharmacy
  • Unlimited protocol adjustments and messaging
  • Ongoing support and check-ins
  • Pause or cancel anytime
  • Reviewed by our in-house physicians
Get Started

How it works

  1. 1.Connect with a physician

    Answer a few questions online and a US-licensed physician reviews your health, history and goals to make sure treatment is right for you. 100% online. No in-person visit required.

  2. 2.Get your discreet shipment

    If approved, your treatment is compounded by a US-licensed, LegitScript-certified pharmacy, inspected for quality, and shipped discreetly to your door.

  3. 3.Receive continuous support

    Start with one goal, then keep building over time. Unlimited physician messaging, easy refills and dose adjustments, all from the Zepym Health app.

Triple PDE5 drops educational content reviewed by our physician

Scott Nass, MDDoctor of Medicine, board-certified in Family Medicine

Charles R. Drew University and David Geffen School of Medicine at UCLA. Family Medicine residency at Ventura County Medical Center.

Frequently asked questions

How do I take Sildenafil / Tadalafil / Vardenafil Drops?

Dissolved under the tongue, once a day. The starting prescription is one ampule each time. Your physician sets your own dose and it is printed on your label.

What strengths does Sildenafil / Tadalafil / Vardenafil Drops come in?

The pharmacy carries 2: 25 mg / 5 mg / 7.5 mg, 40 mg / 4 mg / 15 mg. Your physician chooses which one you get.

What exactly is in it?

Sildenafil, Tadalafil, Vardenafil.

How much arrives in each shipment?

1 bottle at the starting strength, shipped to your door from a licensed US pharmacy.

Do I still need a dose before sex?

Usually not; the daily ampule is meant to keep you ready. Do not add another PDE5 inhibitor without asking your physician.

Can I take it with other medications?

Never with nitrates (nitroglycerin, isosorbide) or recreational poppers: the combination can drop blood pressure dangerously. Tell your physician about alpha-blockers, blood pressure medicines, antifungals and HIV medicines, which change how the drug is processed.

What if it does not work the first time?

Arousal is still required, and a heavy or fatty meal can delay absorption. Most men need two or three attempts at a given dose before judging it. If it still falls short, your physician adjusts the dose or the formulation.

What are the warning signs?

An erection lasting more than 4 hours, sudden loss of vision or hearing, chest pain or fainting need immediate care. Stop the medication and go to the emergency room.

More options, same care.

  • Bi-Mix Injection

    Combination of papaverine and phentolamine for intracavernosal injection. Vasodilator mix for erectile dysfunction. Priapism risk and rescue requirements.

    Injection

    from $171/mo

  • Climax Cream

    Topical cream for female sexual enhancement and orgasm support. Combination of arginine, ergoloid, pentoxifylline, sildenafil, and theophylline.

    Cream

    from $159/mo

  • Ecstasy Cream for Her

    Topical cream for female sexual arousal and pleasure. Contains oxytocin, theophylline, arginine, and sildenafil for enhanced sensation and response.

    Cream

    from $189/mo

Ready to start?

Answer a few questions and take your first step to living well.

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The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Individual results vary.

Sources

  1. 1

    Sildenafil citrate for erectile dysfunction: a systematic review of randomized controlled trials.

    Arch Intern Med, 2002
  2. 2

    Apomorphine SL for erectile dysfunction: randomized, placebo-controlled trials.

    Urology, 2000

from $139/mo

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